Publications by authors named "Asma Mumtaz"

The exciting potential of harnessing the synergy between polysaccharides and bioactive components is attracting significant scientific interest. This research paves the way for the development of novel materials that can improve human health. Therefore, current research is conducted to explore the innovative use of chitosan, polyvinyl alcohol (PVA) complex (CHN-PVA), olive oil-stabilized Pickering emulsions (PEs), and films with multifaceted applications.

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Background: Radio-cephalic arteriovenous fistulas (RC-AVFs), the preferred vascular access for hemodialysis, have high failure rates. New techniques like the no-touch technique (NTT) and modified no-touch technique (MNTT) have shown promising results. Our objective is to highlight the effectiveness of nonconventional techniques, aiming to address the challenge of arteriovenous fistula (AVF) failure.

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Cellulose stabilized multiphase systems (CSMS) have garnered significant attention due to their ultra-stabilization mechanism and vast potential across different fields. CSMS have found valuable applications in scientific disciplines, including Food Science, Pharmaceutical Science, Material Science, and related fields, owing to their beneficial attributes such as sustainability, safety, renewability, and non-toxicity. Furthermore, MPS exhibit novel characteristics that enable multiple mechanisms to produce HIPEs, aerogels, and oleogels revealing undiscovered information.

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Background: Dermatitis is skin disorder that is complicated by recurrent infections of skin by bacteria, viruses, and fungi. Spilanthol is an active constituent of , which possess strong anti-bacterial properties. The purpose of this study was to develop a herbal emulgel for the treatment of dermal bacterial infections, as microscopic organisms have created solid resistance against anti-microbials.

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Article Synopsis
  • * The study focused on creating a new polymer using chitosan and polyethylene glycol (PEG) through a process called PEGylation, successfully producing TAF-loaded nanoparticles confirmed by various analytical methods.
  • * The nanoparticles were about 219.6 nm in size, showed 90% entrapment efficacy, and released about 60% of the drug over 48 hours, indicating potential for TAF delivery, while suggesting that further studies on cytotoxicity and in vivo effects are necessary.
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Objective: is one of the most valuable medicinal plants used for the treatment of hepatic disorders. It is evident that 500 mg/kg of sodium valproate causes the hepatotoxicity, ototoxicity, gastrotoxicity, bone marrow suppression, and inflammation. This study was designed to explore the medicinal uses of in hepatic disorders.

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Murraya koenigii (Mk) is an old plant with a significant therapeutic value throughout Africa, Asia, and Latin America. The excessive use of cisplatin (Cis> 50 mg/m) is associated with nephrotoxicity, ototoxicity, gastrotoxicity, myelosuppression, and allergic reactions. Remedial measures are needed for the protection of nephrotoxicity against cisplatin.

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Background And Purpose: Despite many liver disorders, clinically useful drugs are scarce. Moreover, the available therapies are facing the challenges of efficacy and safety. Alhagi camelorum has been used in folk medicine globally for millennia to treat several ailments.

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SSTIs (Skin and soft tissue infections) are the most commonly occurring infections among all age groups. This study aimed to create an herbal emulgel for the treatment of bacterial skin infections as many bacteria have developed strong resistance against antibiotics. Spilanthe acmella plant extract contains spilanthol which has strong anti-bacterial properties.

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(AC) is an old plant with a significant therapeutic value throughout Africa, Asia, and Latin America. The overuse of cisplatin (Cis > 50 mg/m) is associated with observed nephrotoxicity, ototoxicity, gastrotoxicity, myelosuppression, and allergic reactions. Remedial measures are needed for the protection of nephrotoxicity against cisplatin.

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Article Synopsis
  • The study aimed to evaluate the effectiveness of ligation and excision of femoral artery pseudoaneurysms in intravenous drug users, conducted at a medical center in Pakistan over a four-year period.
  • Out of 119 patients analyzed, the majority were male and the left femoral artery was more commonly affected, with bleeding from the pseudoaneurysm as the primary symptom.
  • Results showed high limb salvage rates (95.8%), low mortality (2.5%), and minimal amputation (1.7%), indicating that surgical intervention without revascularization is an effective treatment.
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Objective To determine the outcomes of the ligation and excision of brachial artery pseudoaneurysm in IV drug abusers without revascularization.  Methodology This retrospective observational study was conducted at the vascular surgery department Shaheed Muhtarma Benazir Bhutto trauma center Karachi from January 2019 to June 2020. All the patients with a history of intravenous drug abuse presented with pulsatile mass at or near cubital fossa, diagnosed as pseudoaneurysm, age ranging from 18-70 years, and of either gender were included in the study.

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Hepatotoxicity is appreciably escalating health dilemma worldwide and the degree of the problem has encouraged importance in the exploration for hepatotherapeutic agents from plants. In the current research work, the hepatoprotective/hepatocurative activity of methanolic extract of Spilanthes acmella Murr aerial parts in paracetamol induced hepatotoxicity was investigated in rabbits by the analysis of different liver enzymes including ALT, AST, ALP along with histopathological investigations. In first phase of the study, paracetamol toxicated rabbits were treated with extract and standard drug jatepar TM.

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