Expression of gene and its promoter activity in MCF control and cancer cells.

Serine/threonine kinase gene () is identified as tumor suppressor gene whose mutation can lead to Peutz-Jeghers syndrome (PJS). STK11 is emerging as a multifunctional protein, it activates 14 different AMP-activated protein kinase (AMPK) family members, important in the regulation of cell polarity, cell cycle arrest, energy and hemostasis. Present study was designed to evaluate mRNA expression in MCF-7 cancer and MCF-10 normal breast cells lines.