Association of the TNF-α, IL-2, and IL-2RB gene variants with susceptibility to psoriasis in a Turkish cohort.

Aim Of The Study: The aim of this study was to investigate the role TNF-, IL-2, and IL-2RB variants in psoriasis (Ps) and to evaluate the association between these variants and clinical features.

Material And Methods: A total of 74 psoriatic patients and 74 healthy individuals were genotyped for these variants by PCR and/or RFLP.

Results: The AA genotype of TNF- (-308) was significantly more common in the patients (p = 0.