Publications by authors named "Asli Zeynep Ozdemir Saltik"

Intensive therapy with exogenous insulin is the treatment of choice for individuals living with type 1 diabetes (T1D) and some with type 2 diabetes, alongside regular glucose monitoring. The development of systems allowing (semi-)automated insulin delivery (AID), by connecting glucose sensors with insulin pumps and algorithms, has revolutionized insulin therapy. Indeed, AID systems have demonstrated a proven impact on overall glucose control, as indicated by effects on glycated hemoglobin (HbA1c), risk of severe hypoglycemia, and quality of life measures.

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Article Synopsis
  • * A cost-utility analysis comparing AHCL to intermittently scanned continuous glucose monitoring (is-CGM) plus multiple daily insulin injections (MDI) showed that AHCL leads to greater quality-adjusted life years (QALYs) gained, despite higher lifetime costs in various European countries.
  • * The study suggests that, even with higher costs, the AHCL system is likely cost-effective for individuals with T1D who are not meeting their glycemic targets using is-CGM and MDI,
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Objectives: The objective was to identify candidate patient reported outcomes with potential to inform individual patient care and service development for inclusion in a digital outcome set to be collected in routine care, as part of an international project to enhance care outcomes for people with diabetes.

Methods: PubMed, COSMIN and COMET databases were searched. Published studies were included if they recommended patient reported outcomes that were clinically useful and/or important to people with diabetes.

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Usage of automated insulin delivery systems is increasing for the treatment of people with type 1 diabetes (T1D). This study compared long-term cost-effectiveness of the Advanced Hybrid Closed Loop MiniMed 780G (AHCL) system versus sensor augmented pump (SAP) system with predictive low glucose management (PLGM) or multiple daily injections (MDI) plus intermittently scanned continuous glucose monitoring (isCGM) in people with T1D in Greece. Analyses were performed using the IQVIA CORE Diabetes Model, with clinical input data sourced from various studies.

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