Publications by authors named "Asli Azami"
Clinical and Genetic Investigation of Premature Ovarian Insufficiency Cases from Turkey.
J Gynecol Obstet Hum Reprod
December 2019
Article Synopsis
- Premature ovarian insufficiency (POI) is defined as the loss of ovarian function in women under 40, and genetic factors may contribute to this condition, particularly in Turkey.
- Researchers analyzed 86 cases of nonsyndromic POI and 26 control participants, focusing on cytogenetic abnormalities and known gene variants associated with POI.
- They identified structural cytogenetic abnormalities in 4.6% of cases and an FMR1 premutation in 2.4%; however, the link to other premature ovarian insufficiency-related genes was weak, indicating that the novel gene variants discovered require further investigation to understand their potential role in POI.