Publications by authors named "Aslan-Kara K"
Introduction: Epilepsy accounts for a substantial part of the global burden of disability. This study aimed to investigate the employment history of people with epilepsy in Türkiye, evaluate the role of education level in employment and epilepsy burden, and compare epilepsy employment data in different societies according to sociodemographic index data.
Methods: This prospective study included 420 people 16-76 years of age who were diagnosed with epilepsy according to the criteria of the International League Against Epilepsy.
Objectives: Juvenile myoclonic epilepsy (JME) is a common form of generalized epilepsy with an important genetic component. This cohort study aimed to examine the frequency of EFHC1 gene variants in Turkish JME patients and a healthy control group and evaluate the association between these mutations and disease risk.
Methods: We screened 72 JME patients with a mean age of 31.
Aim: Isolated REM sleep behavior disorder (IRBD) is characterized by loss of the normal atonia of REM sleep. Patients with IRBD are at substantial risk of developing the synuclein-related neurodegenerative diseases (NDD). Few predictors of phenoconversion (from IRBD to NDD) have been identified such as age >65 years, hyposmia, constipation, elevated Epworth sleepiness scale (ESS).
View Article and Find Full Text PDFObjective: The present study was aimed at investigating the effects of anti-seizure medications (ASMs), patient demographic characteristics, and the seizure type and frequency on the development of congenital malformations (CMs) in the infants of pregnant women with epilepsy (PWWE).
Methods: PWWE followed up at the neurology outpatient clinic of 21 centers between 2014 and 2019 were included in this prospective study. The follow-up of PWWE was conducted using structured, general pregnant follow-up forms prepared by the Pregnancy and Epilepsy Study Committee.
Background: Psychogenic non-epileptic seizures (PNES) resemble epileptic seizures and are often misdiagnosed as epilepsy.
Objective: To investigate the frequency of PNES and to calculate the economic burden of the patients who admitted to video-electroencephalographicmonitoring (VEM) to obtain a diagnosis of epilepsy in order to apply for disability retirement.
Methods: The present retrospective study included 134 patients who required disability reports between 2013 and 2019 and had their definite diagnoses after VEM.
Article Synopsis
- The study investigates the role of KCNQ5 gene variants in genetic generalized epilepsy (GGE) and their link to developmental issues.
- Researchers analyzed genetic data from 1292 families and found several harmful variants associated with GGE and some intellectual disabilities.
- The identified variants lead to a loss-of-function effect in the K7.5 potassium channels, reducing the M-current and possibly increasing neuron excitability, which may contribute to the seizures observed in affected individuals.
Objective: To assess the prevalence of seizure, associated risk factors, and prognosis in patients with SARS-CoV-2 infection and identify predictive biomarkers in SARS-CoV-2 patients with seizure.
Methods: A cohort of 17,806 patients with SARS-CoV-2 infection admitted to two university hospitals in Adana between March 11, 2020 and January 1, 2021 was analyzed retrospectively. The patients' demographic characteristics, laboratory findings, and systemic and neurological symptoms at admission and on the day of seizure onset were evaluated.
Background: To determine the rate of non-convulsive status epilepticus with/without prominent motor phenomena (SE-PM/ NCSE) and predictive value of electroclinical findings of continious electroencephalography (cEEG) monitoring of these patients and its association with prognosis in intensive care units (ICU).
Methods: We retrospectively collected data of 218 patients whose cEEG was performed in ICU between 2016 and 2018. The cEEG for NCSE diagnosis was evaluated according to Salzburg Consensus Criteria (SCC).
Article Synopsis
- The study investigates the relationship between headaches and idiopathic/genetic epilepsy (I/GE) in patients aged 6-40 years, focusing on headache prevalence and characteristics among these individuals.
- Out of 809 patients, 62.8% reported headaches, with 87.4% experiencing interictal headaches and 41.2% having migraines; the analysis identified distinct clusters based on headache and epilepsy features for both adults and children/adolescents.
- Two primary clusters emerged: one included patients with a family history of headaches and specific seizure types (like juvenile myoclonic epilepsy), while the other contained patients with different characteristics, including those with self-limited epilepsy and generalized tonic-clonic seizures. *
Shift work is increasingly common in industrialized countries but is associated with numerous health problems, especially sleep disorders. This study compared the frequency of NREM (confusional arousal, sleep terrors, sleepwalking, sleep-related eating disorder), REM parasomnias (REM sleep behavior disorder, nightmare disorder), and isolated symptoms/normal variants (sleeptalking) between shift workers and daytime workers. A total of 1473 participants in 3 different professional groups and working different shift schedules (daytime, night, or rotating shifts) were included.
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