Drought is a major abiotic factor and affects cereal-based staple food production and reliability in developing countries such as Pakistan. To ensure a sustainable and consistent food supply, holistic production plans involving the integration of several drought mitigation approaches are required. Using a randomized complete block design strategy, we examined the drought-ameliorating characteristics of plant growth-promoting rhizobacteria (PGPR) and nanoparticles (NPs) exclusively or as a combined application (T) through three stages (D, D, and D) of wheat growth (T, control).
View Article and Find Full Text PDFPLoS One
November 2022
Background: Caffeine is available in an ampoule, used via parenteral and enteral routes in preterm neonates to treat apnea of prematurity (AOP) in neonates of gestational age ≥ 35-40 weeks. A longer duration of therapy has a higher risk of medication non-adherence due to higher costs and inappropriate dosage forms. Pharmaceutically compounded oral caffeine (PCC) could be an appropriate alternate dosage form.
View Article and Find Full Text PDFSalicylic acid (SA) is a well-studied phenolic plant hormone that plays an important role in plant defense against the hemi-biothrophic and biothrophic pathogens and depends on the living cells of host for the successful infection. In this study, a pathogenesis test was performed between and cultivars against grape white rot disease (). was found to be resistant against this disease.
View Article and Find Full Text PDFBackground: Peach (Prunus persica L.) is prone to chilling injury as exhibited by inhibition of the ethylene production, failure in softening, and the manifestation of internal browning. The basic leucine zipper (bZIP) transcription factors play an essential role in regulatory networks that control many processes associated with physiological, abiotic and biotic stress responses in fruits.
View Article and Find Full Text PDFThe fabrication of 2D materials and polymer-based nanocomposites deposited on flexible conductive interfaces has unblocked new horizons to expedite reaction kinetics for developing highly selective and sensitive electrochemical biosensors. Herein, we developed a novel biosensing platform, comprising graphene oxide and a silk fibroin-based nanocomposite, drop-cast on a carbon cloth electrode. The fabricated interface was expected to be a robust and miniaturized sensing platform for precise detection of dopamine (DA).
View Article and Find Full Text PDFQuorum sensing (QS) is a major controller of virulence and biofilm formation in pathogenic bacteria. The aim of the research was to screen novel synthetic compounds (18) from 2 series (Pyrazole and Diene dione) for quorum sensing and biofilm inhibitory potential against resistant pathogens isolated from patients with chronic sinusitis. Most of the compounds have documented zone of inhibition against Gram positive strains , and moderate activity against Gram negative and in comparison with standard antibiotic.
View Article and Find Full Text PDFNitrogen (N) is an important macro-nutrient required for crop production and is considered an important commodity for agricultural systems. Urea is a vital source of N that is used widely across the globe to meet crop N requirements. However, N applied in the form of urea is mostly lost in soil, posing serious economic and environmental issues.
View Article and Find Full Text PDFThis work presents the design and fabrication of a metamaterial-based stimulated dual band antenna on FR4 material (dielectric constant 4.3) to operate in Industrial, Scientific and Medical (ISM) and Radio-frequency Identification (RFID) applications. The antenna model had an overall dimension of 70 × 31 × 1.
View Article and Find Full Text PDFAlzheimer's Disease (AD) is a neurological brain disorder that causes dementia and neurological dysfunction, affecting memory, behavior, and cognition. Deep Learning (DL), a kind of Artificial Intelligence (AI), has paved the way for new AD detection and automation methods. The DL model's prediction accuracy depends on the dataset's size.
View Article and Find Full Text PDFTunicamycin inhibits the first step of protein N-glycosylation modification. However, the physiological, transcriptomic, and N-glycomic effects of tunicamycin on important marine diatom Phaeodactylum tricornutum are still unknown. In this study, comprehensive approaches were used to study the effects of tunicamycin stress.
View Article and Find Full Text PDFDisruption of quorum sensing pathway of pathogenic microbes is considered as novel approach to fight against infectious diseases. The current study was planned to evaluate the antibiofilm and quorum sensing inhibitory potential of . Antibacterial and antibiofilm potential of extracts was determined through agar well diffusion and crystal violet assay against sinusitis isolates, that is, , while quorum sensing inhibition efficacy of extracts was determined through violacein inhibition assay using as bacterial model The methanolic extract of presented the highest antimicrobial activity against and antibiofilm activity against (77.
View Article and Find Full Text PDFBackground: Cancer patients are often hesitant to talk about their mental health, religious beliefs regarding the disease, and financial issues that drain them physically and psychologically. But there is a need to break this taboo to understand the perceptions and behaviours of the patients. Previous studies identified many psychological factors that are bothering cancer patients.
View Article and Find Full Text PDFCarbon nanotubes (CNTs) with superior mechanical properties are expected to play a role in the next generation of critical engineering mechanical materials. Crucial advances have been made in CNTs, as it has been reported that the tensile strength of defect-free CNTs and carbon nanotube bundles can approach the theoretical limit. However, the tensile strength of macro carbon nanotube fibers (CNTFs) is far lower than the theoretical level.
View Article and Find Full Text PDFInt J Environ Res Public Health
October 2022
Height-for-age Z-score (HAZ) curves are widely used for detecting children with stunting. The aim of this study was to provide smoothed HAZ growth reference values and their curves for Pakistani children and adolescents aged 2-18 years. The prevalence of stunting in Pakistani children was determined.
View Article and Find Full Text PDFRational design and synthesis of multifunctional electrocatalysts with high electrochemical activity and low cost are significantly important for new-generation lithium-sulfur (Li-S) batteries. Herein, N-doped FeP nanospheres decorated N doped carbon matrix is successfully synthesized by facile one-pot pyrolysis and in-situ phosphorization technique to mitigate the conversion kinetics and suppress the shuttle effect. The large specific surface area with mesopores can incorporate up to 81.
View Article and Find Full Text PDFThe major theme of this analysis is to suggest a new theory in the form of complex picture fuzzy soft (CPFS) information and to initiate their major algebraic laws, score value, and accuracy values. The mathematical form of the CPFS set includes three main functions, called supporting, abstinence, and supporting against terms with a prominent characteristic that the sum of the triplet will lie in the unit interval. Further, in the consideration of the power aggregation operator using generalized t-norm and t-conorm and CPFS information, we diagnosed the mathematical concept of CPFS power averaging (CPFSPA), CPFS weighted power averaging (CPFSWPA), CPFS ordered weighted power averaging (CPFSOWPA), CPFS power geometric (CPFSPG), CPFS weighted power geometric (CPFSWPG), CPFS ordered weighted power geometric (CPFSOWPG).
View Article and Find Full Text PDFUsing the Canadian Myeloma Research Group Database, a retrospective study of 167 newly diagnosed, transplant-ineligible patients with multiple myeloma (MM) that received lenalidomide-dexamethasone as front-line treatment was conducted to understand the impact of lenalidomide dosing. Starting dose modifications were common, 42% of patients started on lenalidomide <25 mg with normal renal function. During treatment course, 35% of patients required further dose reduction.
View Article and Find Full Text PDFBackground: It has been theorized that 75%-80% of febrile neutropenia (FN) is caused by endogenous pathogens, while up to 20% of cases are thought to be caused by a viral infection. It is unknown if precautions such as masking and social distancing reduce the risk of FN in susceptible populations.
Aim: To determine whether coronavirus disease 2019 (COVID-19) infection mitigation efforts, namely masking and social distancing, were associated with a reduction in the incidence of FN.
Background: Bacillus species synthesize antifungal lipopeptides (LPs) making them a sustainable and eco-friendly management option to combat Fusarium wilt of chickpea.
Results: In this study, 18 endophytic Bacillus strains were assessed for their antifungal activity against Fusarium oxysporum f. sp.
Environ Sci Pollut Res Int
February 2023
Dams are studied not only for potential advantages but also for possible environmental repercussions. The objective of this case study is to see the effects caused by Gomal Zam Dam on temperature, humidity and precipitation in their surroundings, both spatially and temporally. The meteorology parameters' characteristics have been detected using two different approaches, Mann-Kendall statistical test and Sen's slope estimator.
View Article and Find Full Text PDFIncreasing antibiotic resistance has shifted researchers' focus to antimicrobial peptides (AMPs) as alternatives to antibiotics. AMPs are small, positively charged, amphipathic peptides with secondary helical structures. They have the ability to disrupt the bacterial membrane and create wedges due to electrostatic differences.
View Article and Find Full Text PDFAccurate patient disease classification and detection through deep-learning (DL) models are increasingly contributing to the area of biomedical imaging. The most frequent gastrointestinal (GI) tract ailments are peptic ulcers and stomach cancer. Conventional endoscopy is a painful and hectic procedure for the patient while Wireless Capsule Endoscopy (WCE) is a useful technology for diagnosing GI problems and doing painless gut imaging.
View Article and Find Full Text PDFTactile sensors are widely used in the electronic industry. In the following research work, we proposed a tactile sensor based on indium zinc oxide (IZO) electrodes and used neutrosophic statistics to analyze the capacitance and resistance of the tactile sensor. The tactile sensor was fabricated by depositing the IZO electrodes on a polycarbonate substrate (a thin layer).
View Article and Find Full Text PDFUV induced DNA damage can lead to the development of skin cancer, skin aging and cell death. In this study, we fabricated a fluorescence-based biosensor that can be applied to the detection of DNA damage caused by UV radiation with the help of nitrogen doped graphene quantum dots (N-GQDs) as the probe material. In this paper, N-GQDs with good fluorescence efficiency have been synthesized by the hydrothermal method and were used as a fluorescent probe for the detection of UV damaged DNA.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
January 2023
This research article examines the impact of stock market capitalization on carbon emissions using forty high carbon-emitting countries from 1996 to 2018. This study adopts the Driscoll-Kraay method that simultaneously tackles heteroscedasticity, autocorrelation, and contemporaneous correlation issues. We find an inverted U relationship between stock market capitalization (SMC) and environmental degradation.
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