Effect of low dose colchicine on long term recurrence after atrial fibrillation ablation.

Background: Colchicine is commonly used early after atrial fibrillation (AF) ablation to reduce inflammation and reduce AF recurrence, but there is limited long-term efficacy data.

Objective: To evaluate the effect of low dose colchicine use on long-term AF recurrence after AF ablation.

Methods: From 2013 to 2021, all AF ablations performed at a single tertiary care medical center were analyzed for colchicine use, clinical and procedural characteristics, and AF recurrence.

A randomised controlled feasibility trial of Behavioural activation as a treatment for people with diabetes and depression: (DiaDeM feasibility trial).

Background: There is a lack of evidence on effective treatments for depression in people with T2DM, particularly in Low and Middle-Income Countries (LMICs). This study aims to test the feasibility and acceptability of a culturally adapted Behavioural Activation (BA) intervention (DiaDeM) for people with depression and T2DM in two South Asian LMICs.

Methods: A multicountry, individually randomised-controlled feasibility trial was conducted from March 2022 to November 2022.

Clinical Application of Pharmacogenomics in the Administration of Common Cardiovascular Medications.

Introduction: Genomic variations among individuals can greatly affect their responses to different medications. Pharmacogenomics is the area of study that aims to understand the relationship between these various genetic variations and subsequent drug responses. Many medications used to optimize cardiovascular health are affected by these genetic variants and these relationships can subsequently impact dosing strategies in patients.

ASSESSING ORONASAL FISTULA RATES: MINIPLATE AS EXTERNAL FIXATOR VS ANTERIOR NASAL SPINE PLATING FOR PALATAL FRACTURES.

Background: Palate, a midface bone, shapes the face and supports buttresses. Palatine process of maxilla and horizontal plate of palatine bone constitute it. Palatal bone is thicker anteriorly and laterally than posteriorly and centrally.

Unprofessional Behavior Among House Officers in Pakistan's Public and Private Hospitals: Prevalence, Perceptions, and Participation.

Background: Professionalism in healthcare is crucial for maintaining patient trust and delivering high-quality care. Unprofessional behaviors among house officers (recent medical graduates undergoing training) raise concerns about their impact on healthcare outcomes. This study aims to assess the prevalence and perceptions of unprofessional behavior, as well as participation in it, among house officers in both public and private hospitals in Pakistan.

First investigation of high-performance FeS-based WO asymmetric supercapacitors operating at 1.6 V.

This study presents a comprehensive evaluation of FeS-WO composite electrodes, revealing their exceptional performance for supercapacitor applications. Fabricated a wet-chemical method, the FeS-WO composites demonstrated a high specific capacitance of 558 F g at a current density of 1 A g, showcasing their outstanding charge storage capabilities. The composites achieved an energy density of 89.

Musculoskeletal Ultrasound Practices of Graduates of a Blended-Learning Program: A Survey of Rheumatologists From the United States.

Objective: Not much is known regarding musculoskeletal ultrasound (MSUS) practices of rheumatologists in the United States. We sought to determine the current use of MSUS among past participants of the Ultrasound School of North American Rheumatologists (USSONAR) training program and, by extension, MSUS-practicing rheumatologists and to understand barriers to its MSUS use.

Methods: An online survey was sent to 374 participants in the eight-month USSONAR blended course (Fundamentals in Musculoskeletal Ultrasound and Train the Trainer) between 2009 and 2020.

The Impact of Intra-abdominal Pressure on Perioperative Outcomes in Laparoscopic Cholecystectomy.

Introduction: Intra-abdominal pressure (IAP) is a critical factor in laparoscopic cholecystectomy, potentially affecting various perioperative outcomes. Understanding the impact of different IAP levels can guide clinical practice to optimize patient safety and recovery.

Objective: This study aimed to evaluate the effects of low, moderate, and high IAPs on perioperative outcomes in patients undergoing laparoscopic cholecystectomy.

Electro-Osmotic Mechanism of Ellis Fluid With Joule Heating, Viscous Dissipation, and Magnetic Field Effects in a Pumping Microtube.

The dynamics of electro-osmotically generated flow of biological viscoelastic fluid in a cylindrical geometry are investigated in this paper. This flux is the result of walls contracting and relaxing sinusoidally in a magnetic environment. The blood's viscoelasticity and shear-thinning viscosity are the primary causes of its non-Newtonian characteristics.

Prevalence of Oral Mucosal Variations in Healthy Elderly Individuals of Taxila City, Pakistan.

Background and objectives Oral mucosal variations, though significant in the aging population, remain under-researched regarding their prevalence and characteristics in local Pakistani population. This study aimed to investigate the prevalence of normal oral mucosal variations in the elderly population, providing insights to aid clinicians and researchers. Methodology This cross-sectional, observational, descriptive study was conducted over four months, from December 2023 to March 2024, in the Department of Oral Medicine at HITEC Institute of Medical Sciences (IMS) Dental College, Taxila, Pakistan.

Soft computing models for prediction of bentonite plastic concrete strength.

Bentonite plastic concrete (BPC) is extensively used in the construction of water-tight structures like cut-off walls in dams, etc., because it offers high plasticity, improved workability, and homogeneity. Also, bentonite is added to concrete mixes for the adsorption of toxic metals.

Enhancing durability and sustainability of industrial floors: A comparative analysis of dry-shake surface hardeners.

This study investigates the development of a cost-effective and sustainable dry-shake surface hardener for enhancing the durability of industrial concrete floors. Utilizing locally sourced materials, the research aimed at not only ensuring the hardener's strength and finish but also its economic viability and environmental friendliness. Fourteen unique mixtures were formulated by altering the sand ratios and incorporating superplasticizers to optimize the composition.

A Case of Traumatic Distal End Radius Fracture With a Hemorrhagic Volar Wrist Ganglion Cyst.

Wrist ganglion cysts are the most common benign soft tissue swelling in the hand and wrist. They may arise from flexor and extensor tendon sheaths, interphalangeal joints, wrist joints, and even the neural tissues around the hand and wrist. Some volar wrist ganglion cysts arise from the radiocarpal joint and scaphotrapezial joint.

Invasive hemodynamic characteristics in patients with mitral annular calcification related mitral stenosis and chest radiation.

Quantification of invasive hemodynamics and mitral annular calcification-related mitral stenosis remains underexplored in patients exposed to chest radiation. We sought to explore invasive hemodynamic parameters via transseptal catheterization in patients with and without chest radiation who had a diagnosis of mitral annular calcification-related mitral stenosis. After excluding patients with more than moderate mitral regurgitation, we found that there was no difference in mitral valve area on hemodynamic testing in patients with and without radiation with an elevated baseline transmitral gradient on transthoracic echocardiography in the setting of mitral annular calcification-related mitral stenosis.

Effects of Proton Pump Inhibitors on Cardiovascular Events and Inflammatory Factors in Patients With Upper Gastrointestinal Bleeding Undergoing Dual Antiplatelet Therapy.

Introduction: Dual antiplatelet therapy (DAPT), vital post-percutaneous coronary intervention (PCI) to prevent cardiovascular events (CVEs) via aspirin and P2Y12 receptor antagonists, faces controversy when combined with proton pump inhibitors (PPIs) due to potential impacts on bleeding risk and antiplatelet efficacy, prompting the need for further research to determine optimal co-administration practices. This work evaluated the effects of PPIs on CVEs and inflammatory factors in patients with upper gastrointestinal bleeding (UGIB) undergoing DAPT after PCI.

Materials And Methods: The data of 166 patients who underwent PCI and developed UGIB while on DAPT from April 2021 to April 2023 were retrospectively analyzed.

Exercise Cardiac Catheterization for Hemodynamic Evaluation of Paradoxical Low-Flow Low-Gradient Severe Aortic Stenosis.

Patients with paradoxical low-flow low-gradient aortic stenosis pose a diagnostic challenge when it comes to assessing the severity of aortic stenosis (AS) noninvasively. We describe 2 patients who underwent exercise cardiac catheterization to augment their cardiac output and assess the severity of AS invasively to allow differentiation of true severe AS from pseudo-severe AS.

Efficient drug delivery potential and antimicrobial activity of biocompatible hydrogels of dextrin/Na-alginate/PVA.

Ceftriaxone sodium belongs to the third-generation cephalosporin group and is used intramuscular and intravenous route as a broad-spectrum antibiotic. This research aims to prepare biocompatible hydrogels for targeted delivery of ceftriaxone sodium by parental route. Different proportions of polymers (natural and synthetic) in the presence of cross-linker were synthesized by solvent casting method.

Anabaena sp. A-1 mediated molybdenum oxide nanoparticles: A novel frontier in green synthesis, characterization and pharmaceutical properties.

Green-synthesized metal oxide nanoparticles have garnered considerable attention due to their simple, sustainable, and eco-friendly attributes, coupled with their diverse applications in biomedicine and environmental context. The current study shows a sustainable approach for synthesizing molybdenum oxide nanoparticles (MoONPs) utilizing an extract from Anabaena sp. A-1.