Publications by authors named "Aslı Arslan"
Article Synopsis
- Vaccines have significantly reduced COVID-19 hospitalizations among adolescents in Turkey, evidenced by a decline in hospitalizations during the vaccination period compared to pre-vaccination.
- The study revealed that while there were more total hospitalizations during the vaccination period, the proportion of vaccinated adolescents requiring hospitalization was lower, reflecting the effectiveness of the vaccine.
- Additionally, breakthrough infections in vaccinated adolescents were generally milder and less severe compared to infections in unvaccinated peers, with many being asymptomatic.
Background: This study focused on timelines of infection episodes and dominant variants and aims to determine disease severity and outcome of pediatric patients with reinfection.
Materials And Methods: This study retrospectively evaluated the medical records of the hospitalized patients and/or outpatients aged 0-18 with a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction between March 2020 and September 2022 at Ege University Children's Hospital.
Results: Ninety-one pediatric patients reinfected with SARS-CoV-2 were included in the study.
The post-COVID-19 syndrome is a new syndrome defined in patients with a history of probable or confirmed SARS-CoV-2 infection, usually within three months of the onset of COVID-19, with symptoms and effects lasting at least 2 months. This study is aimed at comprehensively comparing symptoms of the post-COVID-19 syndrome in children with Delta and Omicron variants. This prospective study included children with COVID-19 followed in hospitalized or outpatient clinics in a tertiary hospital.
View Article and Find Full Text PDFMisdiagnosis of multisystem inflammatory syndrome in children: A diagnostic challenge.
J Paediatr Child Health
April 2023
Aims: As the COVID-19 pandemic continues, multisystem inflammatory syndrome in children (MIS-C) maintains its importance in the differential diagnosis of common febrile diseases. MIS-C should be promptly diagnosed because corticosteroid and/or intravenous immunoglobulin treatment can prevent severe clinical outcomes. In this study, we aimed to evaluate clinical presentation, diagnostic parameters and management of MIS-C and compare its clinical features to those of common febrile disease.
View Article and Find Full Text PDFObjectives: Cardiac manifestations of the coronavirus disease 2019 (COVID-19) have mainly been reported in adults. Therefore, we aimed to determine the electrocardiographic abnormalities in hospitalised paediatric patients with COVID-19 and multisystemic inflammatory syndrome in children.
Methods: We retrospectively evaluated hospitalised paediatric patients <18 years of age with a diagnosis of COVID-19 (n = 168) and multisystem inflammatory syndrome in children (n = 48) between March 2021 and December 2021.
Article Synopsis
- - The study investigated the epidemiological trends of pediatric patients infected with SARS-CoV-2, finding that they generally display milder symptoms than adults but significantly contribute to virus transmission, especially during the delta variant period.
- - Out of 3175 pediatric COVID-19 patients studied, 85.7% experienced at least one symptom, with a notable shift in age demographics as school-aged children and adolescents became more affected when the delta variant emerged.
- - Overall, the research indicated a higher rate of pediatric cases relative to total COVID-19 cases during the delta variant period, and while hospitalization rates increased, the severity of cases requiring PICU admission remained consistent.
Objective: The purpose of this study was to evaluate the relationship of IL28B rs12979860 and rs8099917 polymorphisms with the clinical, histological, and virological outcomes of patients with chronic hepatitis B (CHB) also the treatment responses of patients who received Nucleos(t)ide analogs (NAs) therapy.
Methods: This study included 152 CHB patients who were underwent liver parenchymal biopsy. The IL28B rs12979860 and rs8099917 polymorphism were genotyped using the TaqMan assay.
Background And Aim: This study aimed to detect mutations in the HBV S gene and evaluate their relationship to occult hepatitis B virus (HBV) infection (OBI).
Methods: The study included 32 patients with negative serum HBsAg and HBV DNA who underwent liver biopsy due to different clinical indications defined as the OBI group and 32 patients who underwent liver biopsy due to chronic hepatitis B (CHB) as the comparison group. The HBV S gene region was amplified by Nested PCR, and Sanger sequencing was performed.
Article Synopsis
- Occult hepatitis B infection (OBI) occurs in individuals who test negative for hepatitis B surface antigen (HBsAg) but still have the virus's genome in their liver, indicated by the hepatitis B core antibody (anti-HBc).
- A study of 59 HBsAg-negative chronic hepatitis C patients found OBI in 27.1% of cases, particularly in those who were anti-HBc positive, while none had detectable serum HBV DNA.
- The study suggests that anti-HBc positivity is linked to liver injury progression and recommends screening for anti-HBc in chronic hepatitis C patients to monitor potential complications.
Krebs von den Lungen-6 (KL-6) has been described as a promising biomarker in the diagnosis and determining the severity of interstitial lung disease in adults with connective tissue disease. This study was performed to determine whether the serum KL-6 level is useful as a biomarker for detecting the interstitial lung disease (ILD) in pediatric cases of connective tissue disease (CTD). In total, 88 patients [36 patients with systemic juvenile idiopathic arthritis (sJIA), 27 patients with juvenile systemic lupus erythematosus (JSLE), 14 patients with juvenile dermatomyositis (JDM), and 11 patients with juvenile systemic sclerosis (JSSc)] and 68 healthy controls were included in this study.
View Article and Find Full Text PDFPediatricians' attitudes in management of acute otitis media and ear pain in Turkey.
Int J Pediatr Otorhinolaryngol
April 2018
Objectives: Acute otitis media (AOM) is predominantly a disease of childhood and one of the common reasons for prescribing antibiotics. Ear pain is the main symptom of AOM, with the result that parents frequently seek immediate medical assistance for their children. Antibiotic therapy for AOM does not provide symptomatic relief in the first 24 hours, and analgesics are commonly recommended for relieving the pain associated with AOM.
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