Publications by authors named "Aslı Alkan"

Invasive fungal infection (IFI) is an important cause of morbidity and mortality in acute leukemia patients. In the past few decades, the incidence of IFI has dramatically increased. Nevertheless, the management of IFI has become more complicated owing to changes in the epidemiology of fungal diseases and therapeutic regimens.

View Article and Find Full Text PDF

Background And Aim: Thoracic involvement of Immunoglobulin G4-related disease (IgG4-RD) is relatively rare and may be disregarded at the time of initial diagnosis due to its asymptomatic nature. This study aimed to ascertain the prevalence and patterns of thoracic involvement in a retrospective cohort of Turkish patients with IgG4-RD.

Methods: A total of 90 patients (47 males and 43 females, with a mean age of 57.

View Article and Find Full Text PDF

Objectives: Malnutrition is a clinical condition that is frequently seen in critically ill patients in the intensive care unit (ICU). Although there are many scoring systems and tools used to determine nutritional risk, those that can be used in critically ill patients in the ICU are very few. The scoring systems used are insufficient to identify ICU patients with malnutrition or at risk.

View Article and Find Full Text PDF

Background/aim: Posttraumatic growth (PTG) is defined as positive psychological changes following a challenging or traumatic life event. The purpose of this study is to define the predictors of PTG and death anxiety (DAN) in caregivers of cancer patients and evaluate the impact of DAN on PTG.

Materials And Methods: The caregivers of cancer patients were evaluated using structured questionnaires, including a validated PTG scale and Templer death anxiety scale.

View Article and Find Full Text PDF

Introduction: Controlled hypotension is a reversible procedure in which the patient's baseline mean arterial blood pressure is reduced by 30% and sustained at 60-70 mmHg during the procedure. It decreases blood loss and provides clear surgical field during the procedures.

Objectives: The purpose of this study was to compare the efficacy of controlled hypotension agents esmolol, remifentanil, and nitroglycerin in functional endoscopic sinus surgery, in terms of hemodynamic changes and impact on the surgical efficiency.

View Article and Find Full Text PDF

In this work a new mathematical model, based on non-equilibrium conditions, describing the dynamic adsorption of proteins in columns packed with spherical adsorbent particles is used to study the performance of chromatographic systems. Simulations of frontal chromatography, including axial dispersion, for non-equilibrium systems with non-linear adsorption isotherms are made and compared to those of the experimentally determined protein A affinity chromatography breakthrough curves of hIgG, gathered from the literature. The non-equilibrium model developed here combines external mass transfer and intra-particle transport by solid (surface) diffusion, and permits the prediction of (time and bed height dependent) interface and average solid concentrations, along with interface and bulk liquid concentrations.

View Article and Find Full Text PDF