Theoretical investigations of optoelectronic properties, photocatalytic performance as a water splitting photocatalyst and band gap engineering with transition metals (TM = Fe and Co) of KVO, NaVO and ZnVO: a first-principles study.

First-principles density functional investigations of the structural, electronic, optical and thermodynamic properties of KVO, NaVO and ZnVO were performed using generalized gradient approximation (GGA) ultrasoft pseudopotential and density functional theory (DFT). Their electronic structure was analyzed with a focus on the nature of electronic states near band edges. The electronic band structure revealed that between 6% Fe and 6% Co, 6% Co significantly tuned the band gap with the emergence of new states at the gamma point.

Diagnostic accuracy of low dose CT-Scan abdomen in patients with clinical features of acute appendicitis.

Background & Objective: Acute appendicitis is one of the commonest causes of acute abdominal pain presenting to emergency department (ED) and Computerized Tomography scan (CT) is considered gold standard for its diagnosis. Internationally Low Dose Computerized Tomography scan (LDCT) in emergency department is recommended as a beneficial tool to diagnose acute appendicitis with less exposure to radiation and reduction in the rate of negative laparotomy. Local trials are needed to determine the diagnostic accuracy of LDCT as the first line imaging test for acute appendicitis.

A field-portable electrochemical immunosensor based on a multifunctional AgO/g-CN@MA-DBB covalent organic framework receptor interface for single-step detection of aflatoxin M in raw milk samples.

Aflatoxin M (AFM), a hydroxylated metabolite of aflatoxin B (AFB), contaminates milk and dairy products from livestock ingestion of feed contaminated with a species of . As AFM is a Group-II B carcinogen, it is indispensable to develop novel, easy-to-handle, sensitive, portable and cost-effective strategies for its detection. Herein, a covalent organic framework (COF)-based electroactive nanocomposite, AgO/g-CN-COOH@MA-DBB-COF (silver oxide/carboxy-functionalized graphitic carbon nitride@melamine-dibromo butane COF), is designed to serve as a multifunctional receptor surface.

A Comprehensive on Synthesis and Antimicrobial Evaluation of Substituted-Arylideneamino-5-(5-Chlorobenzofuran-2-yl)-1, 2, 4-Triazole-3-Thiol Derivatives/ Schiff Bases.

Schiff bases are well known and popular classes of organic compounds containing imine (RC = NH) group that are widely used as catalysts and intermediates in numerous organic transformations. Schiff bases are medicinally very important because they exhibit antimicrobial like antibacterial, antiviral and anticancer activities. Benzofuran based Schiff bases have been found as interesting scaffolds for the synthesis and design of biologically active agents.

Dysregulation of Gamma Delta T-Cells, CD8+ T Cells, CD4+ T Cells, and Natural Killer Cells in Brain Pathology: Understanding HIV-Induced Impairment and Exploring Targeted GSH Therapy.

This review comprehensively explores the dysregulation of Gamma Delta T-cells, CD8+ T Cells, and Natural Killer T Cells in the context of Human Immunodeficiency Virus (HIV) infection and its implications for brain pathology. It encompasses an overview of the HIV disease process, immune cell dysregulation, association with neurological diseases, and the critical role of Glutathione (GSH) in T-cell function. The alterations in Gamma Delta T-cells during chronic infection, the intricate dynamics of Vδ1 and Vδ2 subsets, and the potential of Vγ9Vδ2 T cells in inhibiting HIV replication are discussed.

Interplay of interleukins (IL6, IL10) and 25 hydroxycholecalciferol in asthmatic subjects with chronic post-COVID condition (PCC).

The study aimed to compare and correlate serum levels of IL-6, 10, and 25-hydroxycholecalciferol in individuals with asthma with and without post-COVID condition (PCC). The study was designed to investigate the inflammatory response and serum 25-hydroxycholecalciferol status in asthmatics with and without PCC. A cross-sectional study of 252 subjects (128 asthmatics and 124 non-asthmatic subjects) was carried out.

Membranoproliferative Glomerulonephritis Type I Associated with Intravenous Immunoglobulin Administration Arising in a Child with X-Linked Agammaglobulinemia: A Case Report and a Reappraisal.

In 1952, X-linked agammaglobulinemia (XLA) was discovered as a rare inherited disorder. It markedly compromises the ability of the body to combat infectious microorganisms. Membranoproliferative glomerulonephritis (MPGN) Type I is characterized by subendothelial immune complex deposits.

Effect of Intense Pulsed Light versus Intradermal Tranexamic Acid for the Management of Melasma.

Objective: To compare the effectiveness of intense pulsed light (IPL) and intradermal tranexamic acid (TXA) in treating melasma.

Study Design: A cross-sectional analytical study. Place and Duration of the Study: Department of Dermatology, Dow International Medical College, Dow University Hospital, Karachi, Pakistan, from 15th January to 15th July 2023.

Isotretinoin's Effect on Fasting Lipid Profile in Acne Patients.

Objective: To determine the isotretinoin's effect on fasting lipid profile in patients with acne.

Study Design: Observational study. Place and Duration of the Study: Outpatient Department of Dermatology, Dow International Medical College, Dow University of Health Sciences, Karachi, Pakistan, from 22nd June to 21st December 2022.

Improvement in variance estimation using transformed auxiliary variable under simple random sampling.

This paper offers a novel approach to formulate efficient ratio estimator of the population variance using a transformed auxiliary variable. The impact of transformation on auxiliary information has also been discussed. It is observed that incorporating a transformed auxiliary variable result in a high gain in efficiency.

Beyond individual responsibility towards healthy food choices: A qualitative study among Pakistani women in Hong Kong.

While biomedical understandings of food and diet coupled with discourses on individual responsibility towards healthy food choices are nowadays prominent, other social and cultural meanings attached to food and diet are largely devalued. The limits of such a reductionist approach are more evident when related to the experiences of migrant and ethnic populations, whose alternative knowledge(s) and practices about food and health are especially neglected. A multicultural city with a public healthcare system inherited from the British colonial times and largely shaped by biomedical ideas of health, Hong Kong offers a lens into the limits of such a reductionist approach.

The Fluorescence Sensing Capability of 1,4-dihydroxyanthraquinone Towards Metal Ions and Imaging Cells.

Fluorescence and colorimetric sensors have gained significant traction in diverse scientific domains, including environmental, agricultural, and pharmaceutical chemistry. This article comprehensively surveys recent advancements in developing sensors employing 1,4-dihydroxyanthraquinone(1,4-DHAQ). The study delves into the unique properties of 1,4-dihydroxyanthraquinone(1,4-DHAQ) as a sensor, focusing on its capacity to detect Cu ions and elucidating its fluorescence quenching mechanisms.

Ultra-low content physio-chemically crosslinked gelatin hydrogel improves encapsulated 3D cell culture.

Gelatin-based hydrogels are extensively used for 3D cell culture, bioprinting, and tissue engineering due to their cell-adhesive nature and tunable physio-chemical properties. Gelatin hydrogels for 3D cell culture are often developed using high-gelatin content (frequently 10-15 % w/v) to ensure fast gelation and improved stability. While highly stable, such matrices restrict the growth of encapsulated cells due to creating a dense, restrictive environment around the encapsulated cells.

Pair of Functional Polyesters That Are Photo-Cross-Linkable and Electrospinnable to Engineer Elastomeric Scaffolds with Tunable Structure and Properties.

A pair of alkyne- and thiol-functionalized polyesters are designed to engineer elastomeric scaffolds with a wide range of tunable material properties (e.g., thermal, degradation, and mechanical properties) for different tissues, given their different host responses, mechanics, and regenerative capacities.

Effects of Metal Ions and Substituents on HOMO-LUMO Gap Evident from UV-Visible and Fluorescence Spectra of Anthracene Derivatives.

Controlled intake of complex metal cations and anions in the human body and other biological systems is essential for the health and well-being of the environment. Anthracene and anthracene derivatives are the most widely used sensors for this purpose. Because of their convenience, better detection and results are preferred over colorimetric sensors, which offer better color detection by the naked eye.

Investigating the Use of Coumarin Derivatives as Lasers.

A benzene ring and a lactone ring combine to form the chemical coumarin. Dye lasers have made significant advances in laser technology. The coumarin molecule itself is a non-fluorescent but it displays high fluorescence when electron-denoting substituents such as sulfonamide, benzopyrone, amine, benzothiazole, hydroxyl, methoxy are substituted at various positions.

Employee green behavior: a study on the impact of corporate social responsibility (CSR) on employee green behavior, green culture: the moderating role of green innovation.

This study adopts the natural resource-based view (NRBV) of the firm to investigate the relationships between corporate social responsibility (CSR), employees' green behavior (EGB), green culture, environmental performance (EP), and green innovation (GI) in China's automobile manufacturing industry. A survey of 465 employees was conducted. The data were analyzed using partial least squares structural equation modeling.

Effect of Substituents on Solubility, Medicinal, Absorption, Emission and Cationic/Anionic Detection Properties of Anthraquinone Derivatives.

Anthraquinones constitute an important class of compounds with wide applications. The solubility of derivatives at 298.15 K was discussed in ethanol-water solution and at atmospheric pressure, the solubility of 1-amino-4-hydroxy-9,10-anthraquinone (AHAQ) in binary solvents (ethanol-water combinations) was determined.

Metastasis of lung adenocarcinoma to the pituitary gland.

Pituitary metastasis (PM) is rare occurrence and accounts for <1% of all intracranial metastatic lesions. In this study, we highlight the importance of considering atypical sites for lung adenocarcinoma metastasis by presenting a case of a 54-year-old male who was diagnosed with PM 15 months after being diagnosed with stage IV lung adenocarcinoma with metastasis to the spine, pelvis, left frontal lobe, and right occipital lobe. He was on a prolonged course of chemotherapy during those 15 months and received palliative radiation for his brain metastasis with subsequent remission after 5 months following his initial diagnosis.

Exploring the relationships between attitudes toward emission trading schemes, artificial intelligence, climate entrepreneurship, and sustainable performance.

The research objective of this research paper is to examine the relationships between organizational commitment to emission trading schemes, artificial intelligence, and climate entrepreneurship, as well as their impact on sustainable performance, i.e., environmental and organizational performance in organizations.

Effect of Chloride, Sulfate, and Ferrate Salts on Electronic Energy Levels of Anthracene Proving it a Potential Candidate as an ON and ON-OFF UV-Vis Sensor.

Anthracene molecule possesses remarkable optical activity and till today this molecule is of special interest of scientists. Present study is focused on the study of effects of Chloride, Sulfate, Nitrate and Ferrate salts on absorption and emission spectra of targeted fluorophore in carbontetrachloride, chloroform, dichloromethane and methanol. Prominent solvatochromic effects shows dependence of HOMO-LUMO orbitals on solvent polarity.

Association of Vitamin D with Moderate to Severe Acne Vulgaris.

Objective: To determine the association of vitamin D deficiency in moderate to severe acne.

Study Design: A comparative study. Place and Duration of the Study: Dermatology OPD at Dow University of Health Sciences, Karachi, Pakistan, from December 2021 to May 2022.

Spatial-dependent suppressive aftereffect produced by a sound in the rat's inferior colliculus is partially dependent on local inhibition.

In a natural acoustic environment, a preceding sound can suppress the perception of a succeeding sound which can lead to auditory phenomena such as forward masking and the precedence effect. The degree of suppression is dependent on the relationship between the sounds in sound quality, timing, and location. Correlates of such phenomena exist in sound-elicited activities of neurons in hearing-related brain structures.