Publications by authors named "Asim Mohammed"

Article Synopsis
  • The study examined how the volume of heart transplants performed at centers affects their use of Status 2 exceptions, which allow for expedited transplant priority.
  • It analyzed data from the OPTN database for patients who underwent organ heart transplants (OHT) between late 2018 and early 2023, categorizing centers based on their annual transplant volume.
  • Findings showed that lower volume centers applied for Status 2 exceptions much more frequently (50%-60% of the time) compared to medium (30%-35%) and high volume centers (also 30%-35%), indicating that as transplant volume increases, the use of these exceptions decreases significantly.
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The rational design of multiple metal ions into high-entropy oxide electrode material a single-step hydrothermal process is applicable to the evolution of oxygen molecules (O) through simple water electrolysis. Their cost-effectiveness, high performance, and durable nature are the key factors of non-precious high-entropy multiple metal-based electrocatalysts, which can be used as replaceable catalysts instead of precious ones. This article reports a low-temperature synthesis of the cauliflower-type morphology of high-entropy amorphous metal oxides, and their electrochemical performances towards the oxygen evolution reaction (OER) are investigated.

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Article Synopsis
  • - Recent research indicates that using hearts from blood culture positive donors (BCPDs) in pediatric heart transplants is safe and effective, but there’s limited analysis on adult recipients.
  • - A study reviewed over 60,000 donors from 1987 to 2021, finding BCPD hearts had similar short-term survival rates as non-BCPD hearts, but BCPD recipients experienced longer ischemic times and were generally older.
  • - While BCPD recipients showed a potential increase in overall survival and graft function, these results weren't statistically significant, suggesting that careful evaluation of BCPD donors is crucial in heart transplantation.
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The potential for increased rates of morbidity of SARS-CoV-2 within immunocompromised populations has been of concern since the pandemic's onset. Transplant providers and patients can face particularly challenging situations, in the current settings as data continues to emerge for the prevention and treatment of the immunocompromised subpopulation. This case report details a patient 9-months post orthotopic heart transplant that developed SARS-CoV-2 infection despite two prior doses of the Pfizer-BioNtech COVID-19 vaccine, and had successful rescue from refractory hypoxemia with veno-venous extracorporeal membrane oxygenation (VV ECLS).

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Background: Four-factor prothrombin complex (PCC4), a concentrate of factors II, VII, IX, and X and proteins C and S, has been used selectively for reversal of oral anticoagulation before surgery. There is data to support PCC4 as opposed to supplemental fresh frozen plasma (FFP) to manage postoperative bleeding following cardiac surgery. The preemptive, intraoperative use of PCC4 in cardiothoracic surgery has not been studied though it may prevent postoperative bleeding, the need for blood transfusion and the risk of transfusion-related acute lung injury, volume overload, and right ventricular (RV) heart failure.

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Introduction: Recipient functional status prior to transplantation can significantly impact post-transplant survival.

Methods: The United Network for Organ Sharing database was queried for adult heart transplants including data on functional capacity and from February 1, 2005 to March 1, 2021; there were 32 875 cases included. The four functional categories studied were based on adult daily activities of living and were separated into total assistance required, some assistance required, no assistance required, and near death.

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Background: The allocation system for heart donors in the United States changed on October 18, 2018. The typical distance from donor hospitals to recipient hospitals has increased as has the ischemic time. We investigated patient outcomes with the new allocation system and the differential effects of ischemic time under both the old and new allocation schemas.

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Acute respiratory distress syndrome (ARDS) following left ventricular assist device (LVAD) implantation is a rare complication. Venovenous (VV) extracorporeal membrane oxygenation (ECMO) is used as a treatment for severe ARDS and pneumonia. We report the successful use of VV ECMO for ARDS Klebsiella pneumonia following urgent LVAD HeartMate 3 implantation.

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Background: Body mass index (BMI) is an important consideration for transplant-eligible left ventricular assist device (LVAD) recipients. LVAD therapy's impact on BMI is unclear. We evaluated BMI changes in patients who underwent LVAD implantation.

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Cardiac transplant remains the gold-standard treatment for end-stage heart failure more than 50 years after the procedure was first pioneered. The number of transplant operations performed annually has been limited by the global imbalance of donor organs to recipients. This imbalance helped fuel the development of left ventricular assist devices (LVADs) first as a bridge to cardiac transplant and subsequently as destination therapy.

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Despite the widespread belief that donor organ availability varies around holidays and seasons, there is little empirical data supporting this long-held belief. Variations in donor heart availability may be of interest to patients and clinicians. The UNOS/OPTN registry was queried for all heart donations from October 1987 through March 2017.

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We studied whether sustained hemodynamic support (>7 d) with the Impella 5.0 heart pump can be used as a bridge to clinical decisions in patients who present with cardiogenic shock, and whether such support can improve their outcomes. We retrospectively reviewed cases of patients who had Impella 5.

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Background: The objective of this study was to develop a multi-disciplinary care pathway to minimize perioperative complications in patients with advanced heart failure undergoing bariatric surgery. Patients with severe obesity and heart failure carry increased perioperative surgical risk compared to patients with no heart failure due to the severity of their cardiac disease state and associated comorbidities. Our bariatric program routinely excluded patients with advanced heart failure from undergoing bariatric surgery due to the high reported perioperative risk.

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Microaxial left ventricular assist devices (mLVADs) have traditionally been placed through a transfemoral or transaxillary arterial approach. Transfemoral access is restrictive, significantly limiting postoperative patient ambulation. Transaxillary placement is preferred but not feasible in a subset of patients due to small arterial diameter or tight angulation of the thoracic outlet.

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A right ventricular assist device (RVAD) using a dual-lumen percutaneous cannula inserted through the right internal jugular vein (IJV) might improve weaning in patients with refractory right ventricular (RV) failure. However, the reported experience with this cannula is limited. We reviewed the records of all patients receiving RVAD support with this new dual-lumen cannula at our institution between April 2017 and February 2019.

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Aims: 20% to 40% of left ventricular assist device (LVAD) device implantations are complicated by right ventricular (RV) failure that results in significant morbidity and mortality. We hypothesized that the duration on milrinone infusion is an independent risk factor for RV failure following LVAD implantation.

Methods And Results: Retrospective demographic, clinical and hemodynamic data were collected on all adults with ACC/AHA stage D heart failure on intravenous milrinone who underwent LVAD implantation between 2012 and 2019.

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A 64-year-old man being evaluated for pulmonary thromboendarterectomy (PTE) preoperatively experienced pulseless electrical activity secondary to right ventricular failure while undergoing bronchoscopy. After return of spontaneous circulation, a percutaneous right ventricular assist device (RVAD) was placed through the right internal jugular vein. He continued on right ventricular support with demonstration of right ventricular recovery over the following 8 days, and subsequently underwent PTE for treatment of his primary condition.

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Background: Limited national US data are available regarding the prevalence of and trends in different arrhythmias and the use of electrophysiological procedures in patients with alcoholic cardiomyopathy.

Methods: This was a cross-sectional study that used the Nationwide Inpatient Sample database (2007-2014). Hospitalizations of adults with alcoholic CMP were identified with the ICD-9 code (425.

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To analyze predictors of death in elderly patients diagnosed with acute coronary syndrome (ACS). Methods: A record-based study carried out between January 2016 and January 2018 at The central province in Saudi Arabia. All elderly patients (greater than 75 years) with definite diagnosis of ACS were retrospectively included.

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Background: Obese patients with chronic HF have a lower mortality than do non-obese patients with heart failure (HF) i.e. "obesity paradox".

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A 30-year-old man with Marfan syndrome, biventricular heart failure, and an earlier left ventricular assist device placement presented to the emergency department with chest discomfort. Computed tomography with contrast showed contrast extravasation from the anterior aspect of the ascending aorta. The patient was immediately taken to the operating room, where re-exploration of the mediastinum disclosed two needle holes from the distal anastomosis at the toe of the graft that were no longer hemostatic, and it appeared that the patient's heart had dilated in the interim to the point that the outflow graft was too snug.

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Introduction: We aimed to investigate in-hospital outcomes of traumatic brain injury (TBI) based on blood alcohol concentration (BAC) and mechanism of injury (MOI).

Methods: We conducted a retrospective study for patients admitted with TBI between 2010 and 2014. Based on BAC, patients were classified into [negative (-BAC) and positive (+BAC) group].

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Due to an effective synthesis strategy, two kinds of hierarchical porous activated carbons were derived via KOH and HPO activation and carbonization processes from baobab fruit shells (BFSs) used as a green and low-cost biomass precursor. The physicochemical properties and the morphological structure of the baobab fruit shell derived carbons (BFSCs) were systematically studied by scanning electron microscopy (SEM), X-ray diffraction (XRD), Raman spectra, nitrogen adsorption/desorption isotherms and X-ray photoelectron spectroscopy (XPS) techniques. The biomass-derived activated carbons, BFSC1 (using KOH activation), and BFSC2 (using HPO activation), obtained exhibit high specific capacitances of 233.

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Introduction: We aimed to analyze the functional outcomes based on the admission characteristics in individuals with moderate-to-severe traumatic brain injury (TBI) over a 5-year period.

Methods: A retrospective cohort study was conducted to assess the cognitive, physical, and functional outcomes based on traditional and novel metrics used in potential outcome prediction.

Results: A total of 201 participants were enrolled with a mean age of 31.

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