Gone to Guts: Osteosarcoma With Metastasis to Small and Large Intestines Presenting as Recurrent Bleeding.

Gastrointestinal involvement in osteosarcoma is uncommon, with colonic spread being particularly rare. Symptoms range from abdominal pain and obstruction to anemia and melena. Chemotherapy for metastatic lesions has not been standardized, and surgery remains the treatment for selective candidates.

Liposarcoma Masquerading as Immunoglobulin G4-Related Disease.

This case report highlights the challenge of differentiating between immunoglobulin G4 (IgG4)-related disease (IGRD) and liposarcoma, which have similar symptoms and serological markers. A 40-year-old woman presented with right upper-quadrant pain and a retroperitoneal mass. Initial biopsy indicated increased IgG4-positive cells, leading to an IGRD diagnosis.

Chemokine clouding and liver cancer heterogeneity: Does it impact clinical outcomes?

Tumor heterogeneity is a predominant feature of hepatocellular carcinoma (HCC) that plays a crucial role in chemoresistance and limits the efficacy of available chemo/immunotherapy regimens. Thus, a better understanding regarding the molecular determinants of tumor heterogeneity will help in developing newer strategies for effective HCC management. Chemokines, a sub-family of cytokines are one of the key molecular determinants of tumor heterogeneity in HCC and are involved in cell survival, growth, migration, and angiogenesis.

Synergetic Effects of Graphene Nanoplatelets/Tapioca Starch on Water-Based Drilling Muds: Enhancements in Rheological and Filtration Characteristics.

Several borehole problems are encountered during drilling a well due to improper mud design. These problems are directly associated with the rheological and filtration properties of the fluid used during drilling. Thus, it is important to investigate the mud rheological and filtration characteristics of water-based drilling muds (WBMs).