Multicentric Cross-Sectional Survey to Assess the Variation of Fractionation Strategies Used in the Management of Head and Neck Cancers in the Asian Region (INNOCENCE-ASIA).

Purpose: Head and neck cancers (HNCs) are in general treated with conventional fractionation regimen of 1.8-2 Gy per fraction. Altered fractionation (ALFT) strategies such as hypofractionation radiotherapy (HYPO-RT), accelerated fractionation radiotherapy (AFRT), and hyperfractionation radiotherapy (HFRT) have not been practiced uniformly across centers in different parts of the world.

Expression variations of DNA damage response genes ATM and ATR in blood cancer patients.

Hematological malignancies (HM) constitute a variety of cancers originating in blood, bone marrow (BM), and lymphatic systems. During the last two decades, the incidence of HM has dramatically increased worldwide. The etiology of HM is still debatable.

Fyn and Lyn gene polymorphisms impact the risk of thyroid cancer.

Thyroid cancer is the most common malignancy of the endocrine glands, and during last couple of decades, its incidence has risen alarmingly, across the globe. Etiology of thyroid cancer is still debatable. There are a few worth mentioning risk factors which contribute to initiation of abnormalities in thyroid gland leading to cancer.

Role of gene in molecular classification and prognosis of gastric cancer using immunohistochemistry and LORD-Q assay.

The aim of the current study was to assess the prognostic value of the  gene in the DNA damage response pathway in gastric cancer (GC). Expression levels of the were measured in 220 GC tumor tissues and adjacent healthy/noncancerous tissues using real-time PCR and immunohistochemical staining. Genomic instability in GC patients was measured using the long-run real-time PCR technique for DNA-damage quantification assay and comet assay.

Synthesis and characterization of ZnO decorated reduced graphene oxide (ZnO-rGO) and evaluation of its photocatalytic activity toward photodegradation of methylene blue.

Photocatalytic treatment is one of the techniques used for the treatment of dyes-contaminated wastewater. It is important to develop an effective visible-light-driven catalyst for the treatment of dyes-contaminated wastewater. This study reports the synthesis of ZnO-reduced graphene oxide catalyst for the degradation of methylene blue.

Association between single nucleotide polymorphisms of DNA damage response pathway genes and increased risk in breast cancer.

We aimed to evaluate the role of selected single nucleotide polymorphisms of DNA damage response pathway genes in breast cancer (BC). In present study, 500 BC patients and 500 controls was used to estimate the frequency of single nucleotide polymorphisms of DNA damage response pathway genes. Tetra-amplification refractory mutation system-PCR technique was used for screening of the six selected polymorphisms.

Linkage disequilibrium and haplotype analysis of and genes in thyroid cancer.

This study was planned to examine the effects of single nucleotide polymorphism (SNPs) on the risk of thyroid cancer in 499 patients and 500 controls. Three SNPs of gene and three SNPs of gene were analyzed using Tetra-primer ARMS-PCR followed by sequencing. rs121913314 of gene genotype TT showed 32-fold increased risk of thyroid cancer and rs2305994 of genotypes TT and CT showed 2.