How breakthroughs happen: Unearthing the boundary conditions of eco-friendly deliberate practice and eco-innovation performance.

Surprisingly innovation process based on deliberate practice has rarely been unearthed that might explore the boundary conditions of the eco-friendly deliberate practice and eco-innovation performance relationship. Anchored on the organizational support theory and the social cognitive, the current study seeks to investigate the impacts of perceived organizational support (POS) and developmental leadership (DL) on eco-innovation performance (EP) through the mediating role of eco-friendly deliberate practice (EDP). In addition, the study explores the boundary effects of employee resilience (ER) on the relationship between EDP and EP.

Vitamin D status of patients visiting a private endocrinology clinic: a retrospective analysis from Karachi, Pakistan.

Objective: To estimate the burden of vitamin D deficiency and its association with chronic diseases in patients visiting a private endocrinology clinic in an urban setting.

Methods: The retrospective study was conducted at the Medicell Institute of Diabetes Endocrinology & Metabolism, Karachi, and comprised medical records of adult patients of either gender between January 2000 and December 2019.Vitamin D status of the patients and its association with various chronic disorders were investigated.

Comparison of ketoacidosis in type 1 and 2 diabetic patients with and without concurrent COVID-19 and determining the factors affecting their treatment and survival: a retrospective cohort study.

Objectives: To assess the incidence of diabetic ketoacidosis in coronavirus disease-2019 patients and their survival rate, and to compare their outcomes with diabetic ketoacidosis patients without coronavirus disease-2019.

Methods: The retrospective cohort study was conducted at Aga Khan University Hospital, Karachi, and comprised data March 1, 2020, to March 31, 2021, related to patients. who had diabetic ketoacidosis with coronavirus disease- 2019 in group A, and those who had diabetic ketoacidosis without coronavirus disease-2019 in group B.

Coronary Artery Bypass Grafting in Young Adults.

Objective: To evaluate the risk factors for early onset of coronary artery disease (CAD) and assess the preoperative presentation, perioperative course, survival, and short-term complications after coronary artery bypass graft (CABG) in patients aged 45 years or younger undergoing CABG.

Study Design: Observational study. Place and Duration of the Study: Department of Cardiothoracic Surgery, The Aga Khan University Hospital, Karachi, Pakistan, from December 2020 to January 2021.

Lipid-Based Nanoformulations for Drug Delivery: An Ongoing Perspective.

Oils and lipids help make water-insoluble drugs soluble by dispersing them in an aqueous medium with the help of a surfactant and enabling their absorption across the gut barrier. The emergence of microemulsions (thermodynamically stable), nanoemulsions (kinetically stable), and self-emulsifying drug delivery systems added unique characteristics that make them suitable for prolonged storage and controlled release. In the 1990s, solid-phase lipids were introduced to reduce drug leakage from nanoparticles and prolong drug release.

EFFICACY AND SAFETY OF SUPINE PERCUTANEOUS NEPHROLITHOTOMY IN OBESE PATIENTS.

Background: Obesity is an increasing health concern, affecting 39% of the population. In Qatar, in recent years, the obese population contributed 35.9% of men and 46.

The Influence of the Home Food Environment on the Eating Behaviors, Family Meals, and Academic Achievement of Adolescents in Schools in the UAE.

The eating behavior (EB) and habits developed during adolescence tend to persist into adulthood, with parents and caregivers playing a significant role in shaping their children's food choices. The home environment is a crucial setting for developing eating behavior during adolescence. This study aimed to explore the influence of the home food environment (HFE) and its correlates on EB, family meals (FMs), and academic achievement among adolescents in schools in the United Arab Emirates (UAE).

Regional characterization of meteorological and agricultural drought in Baluchistan province, Pakistan.

Drought is a complex natural hazard that occurs when a region experiences a prolonged period of dry conditions, leading to water scarcity and negative impacts on the environment. This study analyzed the recurrence of drought and wet spells in Baluchistan province, Pakistan. Reconnaissance Drought Index (RDI), Standardized Precipitation Evapotranspiration Index (SPEI), and Vegetation Condition Index (VCI) were used to analyze droughts in Baluchistan during 1986-2021.

Phytochemical-mediated regulation of aflatoxigenic fungi contamination in a shifting climate and environment.

Mycotoxin contamination poses a significant problem in developing countries, particularly in northern Pakistan's fluctuating climate. This study aimed to assess aflatoxin contamination in medicinal and condiment plants in Upper Dir (dry-temperate) and Upper Swat (moist-temperate) districts. Plant samples were collected and screened for mycotoxins (Aflatoxin-B1 and Aflatoxin-B-2).

Comparison of Various Therapeutic Approaches to Manage Infertility in Polycystic Ovarian Syndrome.

Objective: To compare the efficacies of common therapeutic regimens and their combinations, used in polycystic ovarian syndrome (PCOS) to improve fertility in reproductive-age women.

Study Design: A descriptive study. Place and Duration of the Study: Department of Obstetric Gynaecologist, Medicare Cardiac and General Hospital, Karachi, Pakistan, from November 2022 to July 2023.

Clinical and genetic investigation of 14 families with various forms of short stature syndromes.

Skeletal dysplasias are a heterogeneous group of disorders presenting mild to lethal defects. Several factors, such as genetic, prenatal, and postnatal environmental may contribute to reduced growth. Fourteen families of Pakistani origin, presenting the syndromic form of short stature either in the autosomal recessive or autosomal dominant manner were clinically and genetically investigated to uncover the underlying genetic etiology.

Novel data visualization and risk analytic algorithm in a low-middle income country.

To discuss the use of T3™, a data aggregation, visualization, and risk analytic platform in a single centre and its framework for implementation of such a tool in clinical care. We share experience of a tool implemented in a tertiary care Intensive Care Unit (ICU) with limited resources. Superusers were identified and trained.

Global trends in hepatitis C-related hepatocellular carcinoma mortality: A public database analysis (1999-2019).

Background: Hepatitis C is the leading cause of chronic liver disease worldwide and it significantly contributes to the burden of hepatocellular carcinoma (HCC). However, there are marked variations in the incidence and mortality rates of HCC across different geographical regions. With the advent of new widely available treatment modalities, such as direct-acting antivirals, it is becoming increasingly imperative to understand the temporal and geographical trends in HCC mortality associated with Hepatitis C.

Breaking the Chain: Strategies to Stem Adenovirus Spread in Pakistan.

Adenovirus, a common respiratory pathogen, has witnessed a notable rise in incidence rates across various regions in Pakistan. Utilizing epidemiological data and climate records, this research discerns a potential linkage between the burgeoning adenovirus cases and alterations in regional climate patterns. Through statistical analysis and modeling techniques, the study aims to elucidate the relationship between climatic variables, such as temperature, humidity, and precipitation, and the prevalence of adenovirus infections.

New record of Philometra species from the marine edible fish Terapon jarbua collected from the Sindh, Arabian Sea, Pakistan.

Diseases in fish due to helminth parasites, especially Philometra species, are the primary worry in aquaculture. Philometra are responsible for health problem in fishes they directly affect fish growth and population parameters. A comprehensive survey was conducted involving the examination of the marine fish species Terapon jarbua, gathered from the coastal waters of Sindh, Pakistan In this research different Philometra species from marine fish Terapon jarbua during 2021 and 2022.

Occupational hazard in urolithiasis patients in Qatar: A single-center cross-sectional study.

Background: Urolithiasis is one of the most prevalent urological diseases and is associated with a substantial economic burden. Its prevalence varies according to geographical location. Qatar is a Middle Eastern country located in the Afro-Asian Stone Belt.

Human biomonitoring of trace metals from different altitudinal settings of Pakistan.

Human biomonitoring of toxic trace elements is of critical importance for public health protection. The current study aims to assess the levels of selected trace metals (Cd, Co, Cr, Cu, Mn, Ni, Pb, and Zn) into paired human nail and hair samples (n = 180 each) from different altitudinal setting along the Indus River, and which were measured by using inductively coupled plasma mass spectrometry (ICP-MS). The human samples (hair and nail) were collected from four different ecological zones of Pakistan which include frozen mountain zone (FMZ), wet mountain zone (WMZ), riverine delta zone (RDZ), and low-lying southern areas (LLZ).

Leading report of molecular prevalence of tick borne Anaplasma marginale and Theileria ovis in yaks (Bos grunniens) from Pakistan.

Domestic yak (Bos grunniens) is an economically important feature of the mountainous region of Gilgit-Baltistan in Pakistan where agriculture is restricted and yaks play multiple roles which includes being a source of milk, meat, hides, fuel and power. However little is known about the parasitic infections in Pakistani yaks. Aim of this research was to report the prevalence and genetic diversity of protozoa parasite (Theileria ovis, 18 S rDNA gene was targeted) and an obligate bacterium (Anaplasma marginale, msp-1 gene was amplified) in the blood that was sampled from 202 yaks collected from four districts in Gilgit-Baltistan during January 2023 till January 2024.

Evaluating Large Language Models for the National Premedical Exam in India: Comparative Analysis of GPT-3.5, GPT-4, and Bard.

Background: Large language models (LLMs) have revolutionized natural language processing with their ability to generate human-like text through extensive training on large data sets. These models, including Generative Pre-trained Transformers (GPT)-3.5 (OpenAI), GPT-4 (OpenAI), and Bard (Google LLC), find applications beyond natural language processing, attracting interest from academia and industry.

Green growth path dependence momentum under the prism of COP26: the role of financial deepening, ICT development, and export diversification.

Financial deepening is important in resource allocation for more productive enterprises, leading to sustainable green growth. Moreover, rapid development in the digital economy and export diversification significantly affect green growth. From this perspective, our study explores the impact of financial deepening, ICT development, and export diversification on green growth in China's economies from 1996 to 2021.

The epidemiology of imported and locally acquired dengue in Australia, 2012-2022.

Background: Dengue is the most important arboviral disease globally and poses ongoing challenges for control including in non-endemic countries with competent mosquito vectors at risk of local transmission through imported cases. We examined recent epidemiological trends in imported and locally acquired dengue in Australia, where the Wolbachia mosquito population replacement method was implemented throughout dengue-prone areas of northern Queensland between 2011 and 2019.

Methods: We analysed dengue cases reported to the Australian National Notifiable Disease Surveillance System between January 2012 and December 2022, and Australian traveller movement data.