Ferric Carboxymaltose as Treatment in Women with Iron-Deficiency Anemia.

. To evaluate safety and efficacy of intravenous ferric carboxymaltose (FCM) versus standard medical care (SMC) for iron-deficiency anemia (IDA) in postpartum women and women with heavy menstrual bleeding. .

Novasure as a mechanical endometrial preparation agent in large uteri.

Objective: We evaluated Novasure ablation as a mechanical endometrial preparation agent before Roller Ball endometrial ablation in lieu of GnRH agonists in large uteri.

Methods: A retrospective chart review of 20 consecutive patients undergoing Novasure ablation for mechanical endometrial preparation before Roller Ball ablation (RBNovasure group) was conducted and the results compared to that of 23 consecutive patients who received GnRH agonist (Leuprolide acetate) as a medical endometrial preparation before Roller Ball ablation (RB-Lupron group). The postoperative follow-up time frame was divided into immediate (3 mo), intermediate (3 to 12 mo) and long-term (12 to 32 mo).

Douching for perceived vaginal odor with no infectious cause of vaginitis: a randomized controlled trial.

Objective: To demonstrate the effectiveness of medical-grade stainless steel Water Works Douching Device for treating abnormal vaginal odor in comparison with a commercially available over-the-counter plastic douching device.

Materials And Methods: In a multicenter study, 140 women with perceived vaginal odor with no vaginal infection were randomized to either Water Works or control group in a 1:1 ratio and were douched daily for 4 weeks. A visual analog scale (VAS) was used to assess the intensity of vaginal odor.

Unusually large extraintestinal GIST presenting as an abdomino-pelvic tumor.

Background: Gastrointestinal stromal tumor (GIST) is a rare visceral tumor that may mimic ovarian tumor.

Case: A 56-year-old woman presented with a large abdomino-pelvic mass and moderately elevated CA-125. A large tumor occupying the whole abdominal cavity and pelvis was noted on laparotomy.

Effectiveness of two tinidazole regimens in treatment of bacterial vaginosis: a randomized controlled trial.

Objective: To assess the effectiveness at 21-30 days after treatment of tinidazole administered orally at 1 g once daily for 5 days and 2 g once daily for 2 days, compared with placebo, in the treatment of bacterial vaginosis, using rigorous U.S. Food and Drug Administration (FDA)-recommended criteria to define cure.

Douching with Water Works device for perceived vaginal odor with or without complaints of discharge in women with no infectious cause of vaginitis: a pilot study.

Objective: To determine if douching with Water Works device for 1 month can (1) lower or eliminate perceived vaginal odor by subject; (2) have any effects on vaginal ecosystem.

Methods: Ten women with perceived vaginal odor with or without discharge, douched every day for 4 weeks in an open-label, nonrandomized pilot study. Primary outcome measures included perceived vaginal odor by subject, lactobacilli score from Nugent slide, and acceptance of the Water Works douching system.

Rapid testing for vaginal yeast detection: a prospective study.

Objective: The purpose of this study was to determine the accuracy of rapid vaginal yeast detection assay compared with yeast cultures for the diagnosis of vulvovaginal candidiasis.

Study Design: This was a prospective study that involved 104 subjects, 34 asymptomatic women and 70 symptomatic women with vaginitis. Vaginal swabs were obtained from all subjects for wet mount, yeast culture, and the rapid yeast detection test.

Resident education regarding technical aspects of cesarean section.

Objective: To survey obstetric/gynecologic residents around the country regarding different technical aspects of and indications for cesarean section, trends in vaginal birth after cesarean (VBAC) and patient choice of cesarean.

Study Design: A questionnaire was designed to address the above issues and selected demographic information. The questionnaire was sent by e-mail to all the residency programs in the country.

Gynecologists' attitudes toward hysterectomy: is the sex of the clinician a factor?

Objective: To assess the effect of gynecologists' sex on their clinical opinions of hysterectomy.

Study Design: A survey presenting a case of symptomatic uterine leiomyomas was randomly mailed to the fellows of the American College of Obstetricians and Gynecologists, who were asked to choose either hysterectomy or any uterus-sparing modality for the treatment of the presented case. The effects of gynecologists' sex, age, race, type and year of training, practice type, location and region on their clinical opinions were evaluated with univariate and multivariate logistic regression analysis.

Adenomyosis interferes with accurate ultrasonographic detection of uterine leiomyomas.

Objective: To evaluate the accuracy of pelvic ultrasonography, and the characteristics of women with inaccurate ultrasonographic diagnosis for uterine leiomyomas.

Materials And Methods: Preoperative pelvic ultrasonographic and postoperative pathologic findings of all women, who underwent hysterectomies for pelvic pain, menorrhagia and/or leiomyomas between December 1995 and July 2002, were evaluated. Three hundred thirty-three women, who had a transabdominal or transvaginal pelvic ultrasonography within 1 year prior to the hysterectomy, were included in the study.

Risk factors for obstetrical anal sphincter lacerations.

The objective of this study was to identify the rate of anal sphincter lacerations in a large population-based database and analyze risk factors associated with this condition. Data were obtained from Pennsylvania Healthcare Cost Containment Council (PHC4) regarding all cases of obstetrical third and fourth degree perineal lacerations that occurred during a 2-year period from January 1990 to December 1991. Modifiable risk factors associated with this condition were analyzed, specifically episiotomy, forceps-assisted vaginal delivery, forceps with episiotomy, vacuum-assisted vaginal delivery, and vacuum with episiotomy.

Risk of recurrence of anal sphincter lacerations.

Objective: To estimate the rate of recurrence of anal sphincter lacerations in subsequent pregnancies and analyze the risk factors associated with recurrent lacerations

Methods: Data were obtained from the Pennsylvania Health Care Cost Containment Council, Division of In-Patient Statistics, regarding all cases of third- and fourth-degree perineal lacerations that occurred during a 2-year period (from January 1990 through December 1991). All subsequent pregnancies in this group of women over the next 10 years were identified, and the rate of recurrence of sphincter tears and risk factors for recurrence were analyzed.

Results: The rate of anal sphincter lacerations was 7.

Hysterectomy in obese women: a comparison of abdominal and vaginal routes.

Objective: To compare perioperative outcome measures of abdominal and vaginal hysterectomies in obese women.

Methods: We reviewed the charts of all obese women (body mass index more than 30 kg/m(2)) who underwent abdominal or vaginal hysterectomy for benign gynecologic conditions in our institution between 1997 and 2002. Laparoscopically assisted vaginal hysterectomies and hysterectomies with concomitant major pelvic or abdominal surgery were excluded.

Narrow pubic arch and increased risk of failure for vaginal hysterectomy.

Objective: The purpose of this study was to evaluate the risk factors involved in failed vaginal hysterectomies.

Methods: Data on all vaginal hysterectomies performed by a single gynecologic surgeon were collected prospectively. Patients requiring pelvic floor repair were excluded.

A case of adenomyosis per se with a uterine weight of 475 g.

Background: Adenomyosis alone usually does not cause significant uterine enlargement.

Case: A 49-year-old woman underwent vaginal hysterectomy and pelvic reconstructive surgery for pelvic organ prolapse. Incidentally, she was found to have adenomyosis with a 475-gram uterus without any other uterine histopathologic finding.

Accuracy of cystoscopy in the diagnosis of ureteral injury in benign gynecologic surgery.

Our objective was to review our experience and attempt to identify risk factors for ureteral injury during gynecologic surgery for benign conditions. A retrospective chart review was performed of all cases of ureteral injury during gynecologic surgery for benign conditions, at Temple University Hospital, from January 1992 to September 2002. We analyzed hospital records to determine whether the injury was diagnosed intraoperatively, with postprocedure cystoscopy, or if cystoscopy was ineffective in diagnosing the injury.

Total colpocleisis for severe pelvic organ prolapse.

Objective: To describe the complications and efficacy of total colpoclesis for severe pelvic organ prolapse.

Study Design: In this descriptive study, we analyzed the complications and efficacy of total colpoclesis in 41 consecutive women with pelvic organ prolapse at Temple University Hospital between November 1994 and June 2001.

Results: The mean followup period was 28.