Evaluation of mrkD, pgaC and wcaJ as biomarkers for rapid identification of K. pneumoniae biofilm infections from endotracheal aspirates and bronchoalveolar lavage.

Klebsiella pneumoniae has been identified as one of the most important opportunistic pathogens responsible for nosocomial infections. Antibiotic resistance and the ability to form biofilms are the two main factors involved in the persistence of infections. Conventional detection methods involve culture isolation and identification followed by biofilm assay that takes 48-72 h.

Genomic Characterization of Mobile Genetic Elements Associated With Carbapenem Resistance of From India.

With the excessive genome plasticity, can acquire and disseminate antimicrobial resistance (AMR) genes often associated with mobile genetic elements (MGEs). Analyzing the genetic environment of resistance genes often provides valuable information on the origin, emergence, evolution, and spread of resistance. Thus, we characterized the genomic features of some clinical isolates of carbapenem-resistant (CRAb) to understand the role of diverse MGEs and their genetic context responsible for disseminating carbapenem resistance genes.

Complete Genome Analysis of Campylobacter jejuni subsp. Isolated from Bloodstream Infection.

We report here the complete genome analysis of a clinical strain sequenced by a hybrid assembly approach. A hybrid assembly approach provided a complete genome sequence of that contains a 1,681,375-bp chromosome and 47,467-bp plasmid carrying various virulence and antimicrobial resistance determinants.

Molecular characterisation for clonality and transmission dynamics of an outbreak of amongst neonates in a tertiary care centre in South India.

Purpose:: Sepsis is a significant cause of morbidity and mortality amongst neonates. Klebsiella pneumoniae is a common cause of nosocomial outbreaks causing bacteraemia and having potential of acquiring plasmids enhancing antimicrobial resistance. In the present study, we investigate K.

First genome report on novel sequence types of Neisseria meningitidis: ST12777 and ST12778.

Objectives: Neisseria meningitidis is an important causative agent of meningitis and/or sepsis with high morbidity and mortality. Baseline genome data on N. meningitidis, especially from developing countries such as India, are lacking.