Case study of thrombosis and thrombocytopenia syndrome following administration of the AstraZeneca COVID-19 vaccine.

Cerebral venous sinus thrombosis is a complication of the ChAdOx1 nCoV-19 vaccine that should elicit a high index of suspicion when patients present with persistent headache post vaccination.

Acute Effects of Ketamine Infusion on Postoperative Mood Scores in Patients Undergoing Dilation and Curettage: A Randomized Double-Blind Controlled Study.

Background: Emotional and psychological effects following abortion are more common than physical side effects and can range from mild regret to more serious complications such as depression. In the last decade, it has been suggested that low dose of ketamine is a fast-acting antidepressant.

Purpose: The aim of this study was to investigate the impact of intraoperative ketamine infusion on postoperative mood score in patients undergoing Dilation and Curettage (D&C) under spinal anesthesia.

Diagnosis of type 2 diabetes using serial fasting plasma glucose versus HbA1c in the primary care setting.

Background And Objective: There are few studies investigating the diagnostic accuracy of type 2 diabetes mellitus (T2DM) by comparing fasting plasma glucose (FPG) with glycated haemoglobin (HbA1c). This proof-of-concept study looked at the correlation between FPG and HbA1c in the early diagnosis of T2DM.

Methods: A case series of 30 consecutive patients met the criteria for T2DM with FPG (>7 mM) or HbA1c (>6.

Safety of regadenoson positron emission tomography stress testing in orthotopic heart transplant patients.

Objectives: We sought to determine the safety of regadenoson (REG) stress testing in patients who have undergone orthotopic heart transplantation (OHT).

Background: Routine screening for cardiac allograft vasculopathy (CAV) is necessary after OHT. Adenosine stress is contraindicated after heart transplantation due to supersensitivity in denervated hearts.

Feasibility of Using Gluconolactone, Trehalose and Hydroxy-Propyl Gamma Cyclodextrin to Enhance Bendroflumethiazide Dissolution Using Lyophilisation and Physical Mixing Techniques.

Purpose: Hydrophobic drugs are facing a major challenge in dissolution rate enhancement and solubility in aqueous solutions; therefore, a variety of methods have been used to improve dissolution rate and/or solubility of bendroflumethiazide as a model hydrophobic drug.

Methods: In this study, two main methods (physical mixing and lyophilisation) were used with gluconolactone, hydroxyl propyl γ-ccyclodextrin, and trehalose to explore this challenge. Bendroflumethiazide, practically insoluble in water, was mixed with one of the three excipients gluconolactone, hydroxyl propyl γ-cyclodextrin, and trehalose in three different ratios 1:1, 1:2, 1:5.

The validity and reliability of the Arabic version of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU): A prospective cohort study.

Background: Accurate diagnosis for Arabic speaking critically ill patients suffering from delirium is limited by the need for a valid/reliable translation of a standardized delirium instrument such as the Confusion Assessment Method for the ICU (CAM-ICU).

Objective: To determine the validity and reliability of the Arabic version of the CAM-ICU.

Design: A prospective cohort study design was used to conduct the current study.

Relationship of non-invasive quantification of myocardial blood flow to arrhythmic events in patients with implantable cardiac defibrillators.

Background: Ischemia contributes to arrhythmogenesis though its role is incompletely understood. Abnormal myocardial perfusion measured by PET imaging may predict ventricular arrhythmias (VAs) in a high-risk population.

Methods: Patients with implantable cardiac defibrillators who had undergone rubidium-82 cardiac PET imaging were identified.

Potential antibacterial activity of some Saudi Arabia honey.

Aim: The aim of this study was to investigate the potential antibacterial activity of some Saudi Arabia honey against selected bacterial strains of medical importance.

Materials And Methods: A total of 10 Saudi Arabia honey used to evaluate their antimicrobial activity against some antibiotic-resistant pathogenic bacterial strains. The bacterial strains were , , , , and .

Cross-sectional study of emergency department presentation triage categories at Goondiwindi Hospital and their effect on the treatment of acute emergencies.

Objective: The objective of this study was to investigate the number and proportion of non-acute presentations to a district hospital emergency department in Goondiwindi, a rural Queensland town, both in the treatment of emergency cases and potential barriers patients have in seeing a medical practitioner in the general practice setting.

Design: Occasions of service to Goondiwindi Hospital were collated from administrative records according to Australasian Triage Scale categories and analysed by Student's t-test for monthly variations in triage category presentations.

Setting: Outpatient clinic (emergency department of a public district hospital).

Safety of regadenoson stress testing in patients with pulmonary hypertension.

Objectives: We sought to determine the safety of regadenoson stress testing in patients with PH.

Background: PH is increasingly recognized at more advanced ages. As many as one-third of patients with PH have coronary artery disease.

Hypochlorite converts cysteinyl-dopamine into a cytotoxic product: A possible factor in Parkinson's Disease.

The dopamine oxidation product cysteinyl-dopamine has attracted attention as a contributor to the death of dopaminergic neurons in Parkinson's disease. Treatment of cysteinyl-dopamine with hypochlorite yields an even more cytotoxic product. This product has potent redox-cycling activity and initiates production of superoxide in PC12 cells.

A Systematic Review of Factors Associated With Utilization of Monitored Anesthesia Care for Gastrointestinal Endoscopy.

Utilization of monitored anesthesia care (MAC) for gastrointestinal endoscopy has increased markedly over the past decade, leading to significant additional health care expenditures. However, the extent to which certain patient-, provider-, and facility-level factors lead to MAC utilization is unclear. A systematic review of 13 studies evaluating influential factors associated with MAC utilization for colonoscopy and/or esophagogastroduodenoscopy was conducted.

Saccharomyces boulardii does not prevent relapse of Crohn's disease.

Background & Aims: Saccharomyces boulardii is a probiotic yeast that has been shown to have beneficial effects on the intestinal epithelial barrier and digestive immune system. There is preliminary evidence that S boulardii could be used to treat patients with Crohn's disease (CD). We performed a randomized, placebo-controlled trial to evaluate the effects of S boulardii in patients with CD who underwent remission during therapy with steroids or aminosalicylates.

Nefopam pharmacokinetics in patients with end-stage renal disease.

Background: Treatment of intense postoperative pain in patients with end-stage renal disease (ESRD) is a recurrent problem for anesthesiologists because of the risk of accumulation of numerous molecules and their metabolites. Nefopam is a potent analgesic metabolized by the liver and weakly eliminated intact in urine that may offer advantages for use in patients with ESRD because it lacks respiratory-depressive effects. However, the effects of renal failure on nefopam disposition have never been investigated.

Cross-sectional study of diet and risk factors for metabolic diseases in a Ghanaian population in Sydney, Australia.

Ethnic groups in affluent environments experience higher rates of metabolic diseases than their native counterparts. Our objective was to determine the prevalence of metabolic risk factors in Ghanaians in Sydney, and to investigate the relationship with dietary and lifestyle factors. Cross-sectional design with anthropometry, blood pressure, plasma lipids, glucose and insulin concentrations were measured on two occasions on each subject.