Incidence of Multidrug-Resistant Organism Among Children Admitted to Pediatric Intensive Care Unit in a Developing Country.

Aim: Multidrug-resistant infections are an increasingly common condition particularly in critical care units. This study aimed to determine the incidence and types of resistant bacteria acquired in a pediatric intensive care unit (PICU) of a university hospital.

Subject And Methods: A prospective study was conducted during the year 2016.

Matrix Metalloproteinase (MMP)-9 Levels in Children on Hemodialysis: Association with MMP-9 CT Gene Polymorphism and Vitamin D Levels.

Background And Objectives: Data concerning the concentration of matrix metalloproteinase-9 (MMP-9) and its functional polymorphisms in chronic kidney diseases (CKD) are conflicting. The present study aimed to evaluate the levels of MMP-9in children with end stage renal diseases (ESRD) on hemodialysis (HD) and to explore its association with MMP-9 polymorphism and vitamin D levels as an important risk factors for cardiovascular diseases (CVD).

Methods: We studied 55 children with ESRD on hemodialysis and 18 healthy children served as controls.

Adipokines Vaspin and Visfatin in Obese Children.

Background: Adipokines provides new insights about the physiology, pathology and treatment of obesity.

Aim: We investigated the association between serum vaspin and serum visfatin concentrations with obesity in Egyptian children.

Material And Methods: Twenty two obese children with body mass index (BMI) above 95th percentile; 11 males and 11 females were included in this study.

The role of anti-Mullerian and inhibin B hormones in the evaluation of 46,XY disorders of sex development.

Objective: To assess the sensitivity and specificity of anti-Mullerian hormone (AMH) and inhibin B for diagnosis of 46,XY disorders of sex development (DSD).

Patients And Methods: The study included 43 patients of 46,XY DSD and compared them with 43 healthy, male, age matched controls. All patients underwent karyotyping, assessment of testosterone, dihydrotestosterone (DHT) and Δ4-androstendione (Δ4A) basal and after human chorionic gonadotropin (HCG) testing.

An SP1-binding site polymorphism in the COLIAI gene and osteoporosis in Egyptian patients with thalassemia major.

β-Thalassemia major is an inherited blood disorder, which mainly affects the Mediterranean region. Osteoporosis represents an important cause of morbidity in β-thalassemia major and its pathogenesis has not been completely clarified. Genetic factors play an important role in the pathogenesis of osteoporosis and several candidate gene polymorphisms have been implicated in the regulation of this process.