Diagnostic Accuracy of Corneal and Epithelial Thickness Map Parameters to Detect Keratoconus and Suspect Keratoconus.

Aim: To establish the diagnostic accuracy of corneal and epithelial thickness measurements obtained by spectral-domain optical coherence tomography (SD-OCT) in detecting keratoconus (KC) and suspect keratoconus (SKC).

Methods: This retrospective study reviewed the data of 144 eyes separated into three groups by the Sirius automated corneal classification software: normal (N) ( = 65), SKC ( = 43), and KC ( = 36). Corneal thickness (CT) and epithelial thickness (ET) in the central (0-2 mm) and paracentral (2-5 mm) zones were obtained with the Cirrus high-definition OCT.

Ray-Tracing Transepithelial Excimer Laser Central Corneal Remodeling Plus Pachymetry-Guided Accelerated Corneal Crosslinking for Keratoconus.

Purpose: The aim of this study was to report the 12 to 96 months results of a tissue-preservation algorithm based on ray-tracing-guided transepithelial excimer laser central corneal ablation (RT t-PRK) combined with individualized pachymetry-guided accelerated crosslinking (M nomogram ACXL) in young adult patients with stable keratoconus (KC).

Methods: This was a prospective interventional study including 38 eyes of 38 young adult patients (stage II KC) with a mean age of 35 years (range 26-46 years) who underwent simultaneous RT with t-PRK plus pachymetry-based ACXL in the worst eye. The treatments were performed using the iViS Suite iRES Excimer Laser (Ligi, Taranto, Italy).

Use of Digital Methods to Optimize Visualization during Surgical Gonioscopy.

The aim of this study was to evaluate the efficacy of digital visualization for enhancing the visualization of iridocorneal structures during surgical gonioscopy. This was a prospective, single-center study on a series of 26 cases of trabecular stent implantation performed by the same surgeon. Images were recorded during surgical gonioscopy, and before stent implantation, with standard colors and with the optimization of various settings, principally color saturation and temperature and the use of the cyan color filter.

Operative Digital Enhancement of Macular Pigment during Macular Surgery.

Purpose: To describe the feasibility of intraoperative digital visualization and its contribution to the enhancement of macular pigmentation visualization in a prospective series of macular surgery interventions.

Materials And Methods: A prospective, single-center, single-surgeon study was performed on a series of 21 consecutive cases of vitrectomy for various types of macular surgery using a 3D visualization system. Two optimized filters were applied to enhance the visualization of the macular pigment (MP).

Evaluation of Anterior and Posterior Corneal Higher Order Aberrations for the Detection of Keratoconus and Suspect Keratoconus.

Aim: To investigate the application of anterior and posterior corneal higher-order aberrations (HOAs) in detecting keratoconus (KC) and suspect keratoconus (SKC).

Method: A retrospective, case-control study evaluating non-ectatic (normal) eyes, SKC eyes, and KC eyes. The Sirius Scheimpfug (CSO, Italy) analyses was used to measure HOAs of the anterior and posterior corneal surfaces.

Transepithelial Enhanced Fluence Pulsed Light M Accelerated Crosslinking for Early Progressive Keratoconus with Chemically Enhanced Riboflavin Solutions and Air Room Oxygen.

Purpose: To assess the 3-year clinical results of the 18 mW 7 J/cm transepithelial enhanced fluence pulsed light M accelerated crosslinking in the treatment of progressive keratoconus (KC) with chemically enhanced hyper-concentrated riboflavin solutions without iontophoresis and with air-room oxygenation.

Setting: Siena Crosslinking Center, Siena, Italy.

Methods: Prospective pilot, open non-randomized interventional study including 40 eyes of 30 young adult patients over 21 years old (10 simultaneous bilateral) with early (Stage I and II) progressive KC undergoing TE-EFPL 18 mW/7 J/cm ACXL (EFPL M TECXL).

Use of Black-and-White Digital Filters to Optimize Visualization in Cataract Surgery.

Purpose: To evaluate the effect of a black-and-white (BW) filter on the optimization of visualization at each stage of cataract surgery.

Methods: Prospective, single-center, single-surgeon, consecutive case series of 40 patients undergoing cataract surgery with BW filter. Surgical images and videos were recorded with and without the BW filter at each stage of cataract surgery.

Facilitating Role of the 3D Viewing System in Tilted Microscope Positions for Cataract Surgery in Patients Unable to Lie Flat.

Purpose: To assess the utility of the 3D viewing system in tilted microscope positions for the performance of cataract surgery in challenging positions, for patients with difficulty remaining supine.

Methods: Prospective, single-center, single-surgeon, consecutive case series of patients undergoing surgery in an inclined position.

Results: 21 eyes of 15 patients who had undergone surgery at inclined positions at angles of 20° to 80°, with a mean angle of 47.

Long term results of accelerated 9 mW corneal crosslinking for early progressive keratoconus: the Siena Eye-Cross Study 2.

Purpose: To assess clinical results of the 9 mW/5.4 J/cm accelerated crosslinking (ACXL) in the treatment of progressive keratoconus (KC) over a span of 5 years.

Methods: The prospective open non-randomized interventional study (Siena Eye-Cross Study 2) included 156 eyes of 112 patients with early progressive KC undergoing the Epi-Off 9 mW/5.

FLACS in Congenital Iris Coloboma: A Useful Technique.

This paper reports the technique and outcome of femtosecond laser-assisted cataract surgery (FLACS) in an iris coloboma patient (59-year-old male patient) with bilateral grade 3 cataractous lens and a shallow anterior chamber. Best-corrected visual acuity (BCVA) was 0 on logMAR with spherical equivalent (SE) 9 D in the right eye, and BCVA of 0.3 logMAR with a SE 8.