Quality of obturation achieved by an endodontic core-carrier system with crosslinked gutta-percha carrier in single-rooted canals.

Objectives: The present study examined the quality of obturation in root canals obturated by GuttaCore, a gutta-percha-based core-carrier system with a cross-linked thermoset gutta-percha carrier, by comparing the incidence of gaps and voids identified from similar canals obturated by cold lateral compaction or warm vertical compaction.

Methods: Thirty single-rooted premolars with oval-shaped canals were shaped and cleaned, and obturated with one of the three obturation techniques (N=10): GuttaCore, warm vertical compaction or cold lateral compaction. Filled canals were scanned with micro-computed tomography (micro-CT); reconstructed images were analysed for the volumetric percentage of gaps and voids at three canal levels (0-4mm, 4-8mm and 8-12mm from working length).

Effects of tricalcium silicate cements on osteogenic differentiation of human bone marrow-derived mesenchymal stem cells in vitro.

Tricalcium silicate cements have been successfully employed in the biomedical field as bioactive bone and dentin substitutes, with widely acclaimed osteoactive properties. This research analyzed the effects of different tricalcium silicate cement formulations on the temporal osteoactivity profile of human bone marrow-derived mesenchymal stem cells (hMW-MSCs). These cells were exposed to four commercially available tricalcium silicate cement formulations in osteogenic differentiation medium.

In vitro biocompatibility and oxidative stress profiles of different hydraulic calcium silicate cements.

Introduction: MTA Plus is a new calcium silicate cement with unknown cytotoxicity characteristics. The objectives of this study were to examine the effect of MTA Plus on the viability, apoptosis/necrosis profile, and oxidative stress levels of rat odontoblast-like cells.

Methods: MDPC-23 cells were exposed to gray and white MTA Plus (GMTAP, WMTAP), gray and white ProRoot MTA (GMTA, WMTA) cements, or their eluents.

Ability of new obturation materials to improve the seal of the root canal system: a review.

New obturation biomaterials have been introduced over the past decade to improve the seal of the root canal system. However, it is not clear whether they have really produced a three-dimensional impervious seal that is important for reducing diseases associated with root canal treatment. A review of the literature was performed to identify models that have been employed for evaluating the seal of the root canal system.

In vitro osteogenic/dentinogenic potential of an experimental calcium aluminosilicate cement.

Introduction: Calcium aluminosilicate cements are fast-setting, acid-resistant, bioactive cements that may be used as root-repair materials. This study examined the osteogenic/dentinogenic potential of an experimental calcium aluminosilicate cement (Quick-Set) by using a murine odontoblast-like cell model.

Methods: Quick-Set and white ProRoot MTA (WMTA) were mixed with the proprietary gel or deionized water, allowed to set completely in 100% relative humidity, and aged in complete growth medium for 2 weeks until rendered non-cytotoxic.

Time-based lateral hygroscopic expansion of a water-expandable endodontic obturation point.

Objectives: This study compared the time-based lateral expansion of two sizes and two batches of water-expandable obturation points (CPoint, EndoTechnologies, LLC) and a similar-sized gutta-percha point (control) at various distances from the point apex: 5, 10, and 15mm.

Methods: Two batches of sizes 25 and 40 (0.06 taper) CPoints and a single lot of size 40 (0.

In Vitro biocompatibility evaluation of a root canal filling material that expands on water sorption.

Introduction: CPoint is a polymeric endodontic point that takes advantage of water-induced, non-isotropic radial expansion to adapt to canal irregularities. This study evaluated the effects of CPoint on the viability and mineralization potential of odontoblast-like cells.

Methods: The biocompatibility of CPoint and commercially available gutta-percha points was evaluated by using a rat odontoblast-like cell line (MDPC-23).

Wall shear stress effects of different endodontic irrigation techniques and systems.

Objectives: This study examined débridement efficacy as a result of wall shear stresses created by different irrigant delivery/agitation techniques in an inaccessible recess of a curved root canal model.

Methods: A reusable, curved canal cavity containing a simulated canal fin was milled into mirrored titanium blocks. Calcium hydroxide (Ca(OH)2) paste was used as debris and loaded into the canal fin.

Periapical pressures developed by nonbinding irrigation needles at various irrigation delivery rates.

Introduction: Injection of sodium hypochlorite (NaOCl) from the root canal into periapical tissues may result in a NaOCl incident. The purpose of this study was to examine the fluid pressure generated by canal cleansing devices at the apical interface, when the tip of the irrigation device was not binding to the canal walls.

Methods: Apical pressure was monitored in a closed-system root canal model, with NaOCl delivered by a syringe pump at 0.

Characterization of the mineral trioxide aggregate-resin modified glass ionomer cement interface in different setting conditions.

Introduction: Mineral trioxide aggregate (MTA) has been used successfully for perforation repair, vital pulpotomies, and direct pulp capping. However, little is known about the interactions between MTA and glass ionomer cement (GIC) in final restorations. In this study, 2 null hypotheses were tested: (1) GIC placement time does not affect the MTA-GIC structural interface and hardness and (2) moisture does not affect the MTA-GIC structural interface and hardness.