Publications by authors named "Ashpole R"

Article Synopsis
  • This paper highlights the collaboration of researchers, individuals with traumatic brain injury, and health professionals to adapt WHO physical activity guidelines for people with moderate-to-severe traumatic brain injury in Australia.
  • Through a structured four-stage approach, the team identified and refined key attributes related to physical activity preferences, reducing the initial 17 factors to six essential categories.
  • The process also focused on improving the survey’s clarity and relevance, addressing challenges in recruitment and language to ensure meaningful input from diverse stakeholders.
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Background: The Neurology and Neurosurgery Interest Group (NANSIG) neurosurgical skills workshop is novel in teaching neurosurgical skills solely to medical students and foundation trainees in the UK. The aim is to offer an affordable option for a high-fidelity simulation course enabling students to learn and practise specific neurosurgical skills in a safe, supervised environment.

Methods: A 10-delegate cohort was quantitatively assessed at the NANSIG neurosurgical skills workshop.

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We present the case of a 66 year old gentleman with trigeminal schwannoma whose only presenting feature was a single gelastic seizure. This is the first case report of pathological laughter in trigeminal schwannoma in the absence of other trigeminal, brainstem, cerebellar or other cranial nerve dysfunction.

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The Neurology and Neurosurgery Interest Group (NANSIG), the student arm of the Society of British Neurological Surgeons (SBNS), organised a neurosurgical skills workshop in January 2017 following evidence of high demand among medical students and foundation trainees. The workshop involved ten delegates and five neurosurgical trainees with one senior consultant. Modules covering head positioning, burr holes, ventricular access, and flaps were included.

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We report a case of dangerous combustion of Tantalum/Onyx embolic agent when exposed to mono-polar diathermy during subsequent surgical resection of a partially embolised arteriovenous malformation. Surgeons should be aware that previous embolisation of a vascular malformation may make use of diathermy problematic if subsequent surgical management is required.

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Background: We report our experience with the minimally invasive supraorbital approach to aneurysms of the ipsilateral anterior cerebral circulation.

Methods: A prospective review of all patients who underwent operations to clip aneurysms in Newcastle between 1993 and 2002.

Results: Fifty-six aneurysms were clipped via minicraniotomy in 47 patients.

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Rheumatoid disease is a systemic disorder affecting multiple organs. It is known to affect the nervous system in a variety of ways, but its presentation with spinal cord compression by a rheumatoid nodule is rare. We report two cases presenting with cord compression by a rheumatoid nodule who underwent surgical decompression with good recovery.

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In the UK there are currently great changes taking place in both higher surgical training and consultant practice. Australia inherited the British system, many aspects of which it retains, but has moved to a US type training programme. Recent experience of British and Australian neurosurgical practice allows useful comparisons to be made with possible benefit to both.

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Objective: To examine the nature and frequency of anterior temporal lobe (AT) abnormalities that occur in intractable temporal lobe epilepsy (TLE).

Methods: We reviewed the MR scans and clinical histories of 50 consecutive patients with intractable TLE. Histopathology was available in 42 surgically treated cases.

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We report a case in which a balloon detached in the carotid siphon for control of iatrogenic bleeding migrated to the oesophagus. We discuss the pathophysiology.

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A disadvantage of stereotactic placement of flexible depth electrodes is the risk of inaccurate positioning as a result of electrode movement when the introducer is withdrawn. A simple device that virtually eliminates this error is described.

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Over 30 cases of perforation of the bowel have been described by intact peritoneal catheters of ventriculo-peritoneal and some lumbo-peritoneal shunts. Because of this risk it is advocated that redundant or free fractured or disconnected peritoneal catheters should if possible be removed from the abdomen; although we could find no reports of morbidity from such free fragments. We describe a case of extrusion per-rectum of a redundant fractured peritoneal catheter which it had not been possible to retrieve after a revision procedure.

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Ten patients with neoplastic meningitis were treated with a variety of 131I-monoclonal antibody (MAb) conjugates, chosen to bind to their particular malignancy. Pharmacokinetic studies revealed that MAbs leave the ventricular compartment, enter the sub-arachnoid space and then pass into the blood. Once the MAbs enter the blood compartment, their clearance is determined by factors such as circulating anti-mouse Ig and circulating antigens.

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In modern neurosurgery there are many types of ventricular shunts, ventricular drains and access devices. These are composed of a variety of components which are best assembled and manipulated using a non-touch technique. A comprehensive and inexpensive set of instruments is described which is easy to sterilize and which will facilitate the easy manipulation and assembly of a wide range of these devices by a true non-touch technique.

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Seven patients with carcinomatous meningitis were administered intrathecal I-131 labelled monoclonal antibody HMFG1. Clinical responses were seen in two patients, with a long term survivor at 32 months. Aseptic meningitis occurred in 4/7 patients, but more serious toxicity was observed in the form of seizures (2/7 patients) and myelosuppression (3/7 patients).

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Infection is a frequent problem affecting cysto-peritoneal shunts, the usual causative organisms being Staphylococcus epidermidis and Staphylococcus aureus. Fungi are rarely isolated from such infections. We present the first report, as far as the authors are aware, of a case of Trichosporon beigelii shunt infection that responded to shunt removal and antifungal therapy.

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Failure of conventional treatment to cure malignant gliomas has stimulated interest in various forms of brachytherapy. We describe a new method of using intracranial radiation utilizing a remotely-controlled afterloading system with a modified endotracheal tube as the applicator. The system used is the Selectron LDM/MDR (Nucleotron) which is a sophisticated machine widely available at radiotherapy centres and primarily used to treat gynaecological malignancies.

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