A Comparative Study of Interventions of Middle Turbinate Medialization in Endoscopic Sinus Surgery.

The shape and position of middle turbinate play an important role in ventilation and drainage of the osteomeatal complex. The preservation of middle turbinate is one of the major goals of functional endoscopic sinus surgery (FESS). Middle turbinate intervention is essential to prevent obliteration of osteomeatal complex.

Systems biology approach delineates critical pathways associated with disease progression in rheumatoid arthritis.

Rheumatoid Arthritis (RA) is a chronic systemic autoimmune disease leading to inflammation, cartilage cell death, synoviocyte proliferation, and increased and impaired differentiation of osteoclasts and osteoblasts leading to joint erosions and deformities. Transcriptomics, proteomics, and metabolomics datasets were analyzed to identify the critical pathways that drive the RA pathophysiology. Single nucleotide polymorphisms (SNPs) associated with RA were analyzed for the functional implications, clinical outcomes, and blood parameters later validated by literature.

Role of Computed Tomography Findings in the Quest of Understanding Origin of Antrochoanal Polyp.

Aetio pathogenesis of antrochoanal polyp (ACP) remains unclear. Correlation of clinical, computed tomography (CT) and histopathological findings is attempted in this study for understanding of their origin. A retrospective chart and image review of 22 patients having ACP was done for clinical, histopathological and CT findings on affected and non affected side for extent of opacificattion, thickness of alveolar bone (AB) in the region of medial wall and the floor of maxillary sinus.

Acquired Angioedema: A Rare Manifestation of Angioimmunoblastic T Cell Lymphoma.

The clinical presentation except age of onset is similar in different types of angioedema. A lymphoproliferative disorder like angioimmunoblastic T cell lymphoma (AITL) rarely presents with symptoms of angioedema. We present extremely rare case of elderly male with recurrent tongue swelling, pruritus with normal levels of complements and C1 esterase inhibitor protein featuring as acquired angioedema, a rare manifestation of AITL.

Detection of bacteria by 16S rRNA PCR and sequencing in culture-negative chronic rhinosinusitis.

Objective: Current studies on the association between bacteria and chronic rhinosinusitis (CRS) have relied solely on microbiological culture, which can sometimes be negative due to prior antibiotic therapy or lack of transport media. The objective of the study was to understand whether bacteria are associated with culture-negative cases.

Methods: We investigated 20 cases of CRS undergoing functional endoscopic sinus surgery by both culture and 16S rRNA gene polymerase chain reaction (PCR) followed by sequencing.

Bacterial Biofilms in Chronic Rhinosinusitis and Their Implications for Clinical Management.

To study the microbiological profile in patients with chronic rhino-sinusitis. To correlate disease severity with the presence of biofilms and host risk factors. To assess outcome of Sinus Surgery 2 weeks post operatively in terms of presence of bacteria and their ability to form biofilm.

Improving the Diagnosis of Scrub Typhus by Combining Based Polymerase Chain Reaction and IgM ELISA.

Introduction: Scrub typhus, an acute febrile illness, caused by , is an important cause of pyrexia of unknown origin in regions of endemicity. This disease is mostly underdiagnosed or misdiagnosed, the reasons for this being a combination of factors which include clinical manifestations that can mimic other infections, lack of easy and reliable diagnostic methods and variation among strains in endemic areas. Hence, easy and reliable methods of diagnosis will contribute to rapid identification and treatment of the infection.

Perioperative only versus extended antimicrobial usage in tympanomastoid surgery: a randomized trial.

Objectives/hypothesis: Antimicrobial prophylaxis is still a matter of debate in ear surgeries. Previous studies have focused on prophylaxis in middle ear surgery alone without inclusion of mastoidectomy. We therefore investigated efficacy of two regimes of antimicrobial prophylaxis in tympanoplasty with cortical mastoidectomy done for mild middle ear disease in chronic otitis media.

Short Anagen Syndrome in an Indian Woman with its Impact on Quality-of-Life.

Short anagen syndrome (SAS) is a recently described entity characterized by idiopathic shortening of anagen phase. The condition is poorly described in Indian population. We describe the 1(st) Indian case with clinico-pathological features of a 30-year-old woman diagnosed with SAS.

Klebsiella-associated phagedenic ulcers in infants-a report of two cases.

Phagedenic ulcer is usually associated with infections due to staphylococcus, pseudomonas, streptococcus or fusospirochete in immunocompromised individuals. We report, for the first time, two cases of phagedenic ulcers in infants caused by Klebsiella pneumonia species.

Role of nasal endoscopy in chronic osteomyelitis of maxilla and zygoma: a case report.

Osteomyelitis of the jaws was relatively common before the era of antibiotic therapy and preventive and restorative dentistry. Osteomyelitis is an acute or chronic inflammatory process that can involve cortical and trabecular aspects of bone or bone marrow. Cranial bones are infrequently involved, but spreading of inflammation with involvement of surrounding structures represents important risk, such as cerebral abscess, encephalitis, or meningitis.

Chromoblastomycosis presenting as a phagedenic ulcer on the face.

Background: Chromoblastomycosis is a chronic fungal infection which presents as a small ulcer, plaques, papulonodular lesion to cauliflower-like warty masses and cicatricial forms. The disease is relatively uncommon, with only a few published case report.

Methods: A 35-year-old female presented with phagedenic ulcer on the face since 15 years.

Foreign bodies in upper digestive tract.

Foreign body ingestion is a common problem frequently encountered in both children and adults. A total number of 152 patients (104 children and 48 adults) with ingested foreign body admitted in our hospital are reviewed. Location of foreign body was made out by radiological examination.

Choanal atresia: Experience with transnasal endoscopic technique.

Congenital choanal atresia has been recognized for over 200 years, first described by Roederer in 1775 (Lantz and Brick, Laryngoscope 91, 1981, 1626. Samuel and Fernandes. Laryngoscope 95, 1985, 326).

Bronchial foreign bodies.

Foreign body aspiration is an extremely serious problem in childhood with varied clinical presentation demanding high degree of suspicion on the part of clinician. Surgical emphysema of the neck and chest often complicates tracheostomy and sharp penetrating injuries to the neck perforating viscera of the aerodigestive tract. Rarely if follows chest injuries.

Foreign body in upper digestive tract.

Objective: Foreign body ingestion is a common clinical problem, encountered in children.

Methods: A total number of 104 patients with ingested foreign body admitted in our hospital are reviewed. Endoscopic removal was done for all foreign objects impacted in esophagus.

Lipoma of the retropharyngeal space.

Lipoma in retropharyngeal space is rare. A case of lipoma in the retropharyngeal space of a paediatric patient is reported with characteristic radiological findings along with surgical management.

Choanal atresia: transnasal endoscopic technique.

Objective: This article attempts to address the controversy between, endoscopic and traditional approaches to neonatal choanal atresia.

Method: Congenital choanal atresia has been recognized for over 200 years, first described by Roedere in 1775. This condition is uncommon, occurring in approximately 1 in 7000 live births.

Tracheobronchial foreign bodies.

Objective: [corrected] Foreign body inhalation is an extremely serious problem in children and sometimes result in sudden death. The current mortality rate from foreign body inhalation is between 0% and 1.8% according to various studies.

Unusual foreign body in the trachea.

A great variety of foreign bodies in the traeheohr onvhial tree have been reported, but presence of fractured tracheostomy tube as foreign body is ran1. Usually fractured pieces of outer tube are found in the bronchus or trachea near the carina, but occurence of inner tube in the upper part of the trachea is rare2 and one such case is presented here.