Severe asthma can be associated with eosinophilic or allergic phenotypes or both. Eosinophilic inflammation is associated with exacerbations and disease severity due to biological activity of interleukin-5 (IL-5). Patients with severe asthma have reported reduced lung function and poor health-related quality of life (HRQoL) and may require systemic corticosteroids for its management.
View Article and Find Full Text PDFChylothorax is one of the presenting features in many disorders including malignancy. Thorough investigation is often required for establishing the etiology of chylothorax. Unfortunately, despite appropriate work-up etiology of pleural effusion cannot be established.
View Article and Find Full Text PDFJ Bronchology Interv Pulmonol
January 2014