Endoscopic ultrasonography-guided coil embolization and cyanoacrylate injection versus cyanoacrylate injection alone for gastric varices: a randomized comparative study.

Background: Bleeding from gastric varices is life-threatening, with significant rebleeding risk despite standard cyanoacrylate glue injection therapy. Our aim was to evaluate the efficacy and safety of endoscopic ultrasonography (EUS)-guided coil embolization with cyanoacrylate injection (Coil+CYA) compared with EUS-guided cyanoacrylate injection alone (CYA) for the treatment of gastric varices.

Methods: The study was conducted at a tertiary referral center in India, using a single-blinded, prospective, and parallel-group randomized design.

Intravenous versus oral 'L-ornithine-L-aspartate' in overt hepatic encephalopathy: a randomized comparative study.

Hepatic encephalopathy (HE), a morbid ordeal affecting chronic liver disease patients always insists for the search of a rational, superior & infallible agent beyond the time-proven standards i.e., Lactulose & Rifaximin.

Efficacy and Rationale of Endoscopic Ultrasound-Guided Thrombin Injection in Visceral Artery Pseudoaneurysm Not Amenable to Angioembolization.

Background: Pseudoaneurysm usually occurs after vascular injuries or erosions such as in trauma or inflammation like pancreatitis and is associated with high morbidity and mortality.

Aim: The aim of study is to assess efficacy and safety of EUS-guided thrombin injection in pseudoaneurysm.

Materials And Methods: Prospective data collection was done at SMS Hospital, Jaipur, from January 2015 to March 2023.

Endoscopic Glue Injection Versus Endoscopic Human Thrombin Injection for Bleeding Gastric Varices-A Randomized Controlled Trial.

Background: Acute gastric variceal bleeding (AGVB) is a potentially fatal consequence of portal hypertension, accounting for 10% to 30% of all variceal bleeding. Although endoscopic cyanoacrylate glue injection is a common treatment for acute hemostasis, it has been linked to significant side effects. In the treatment of AGVB, there is limited evidence of the efficacy and relative safety of endoscopic human thrombin injection over glue injection.

Evaluating the efficacy of nitazoxanide in uncomplicated amebic liver abscess.

Background: Amebic liver abscess is treated successfully with metronidazole or another nitroimidazole drug followed by a luminal amebicide. Metronidazole has long been preferred, but has been associated with several adverse effects including intolerance in certain clinical situations. Mechanisms of metronidazole resistance and mutagenic potential have been described.

Celiac Disease and Portal Hypertension: A Causal Association or Just a Coincidence?

Introduction: Celiac disease (CD) has been linked to portal hypertension (PHT) of varied etiology, but the causality association has never been proved. We aim to study the prevalence of CD in patients of PHT of different etiology.

Methods: A prospective observational study was conducted from June 2017 to December 2018 involving all the cases of PHT of varied etiology.

Role and safety of human thrombin injection for the treatment of bleeding gastric varices.

Background: Human thrombin appears to be a new effective tool in the armamentarium of management of bleeding gastric varices, but there are paucity of data on its use. Thus, we share our experience with human thrombin in the treatment of bleeding gastric varices.

Methods: It was a prospective interventional study conducted between September 2015 and December 2017.

Endoscopic ultrasound-guided thrombin injection for management of visceral artery pseudoaneurysm: A novel approach.

Visceral artery pseudoaneurysm is a rare and potentially life-threatening vascular entity with a high mortality rate, conventionally managed with digital subtraction angiography with coil embolization or surgery. However, in cases where angiographic coil embolization is not possible due to technical reasons, computerized tomography (CT)/ultrasonography-guided thrombin injection remains a viable option as described in the literature. In this case series, we intend to highlight the role of endoscopic ultrasound-guided thrombin injection in the management of abdominal visceral artery pseudoaneurysm, which is either inaccessible by endovascular route or have high surgical risk of complication.

Endoscopic management of pancreatic pseudocysts and walled-off pancreatic necrosis: A two-decade experience.

Aim: To determine long-term outcome of endoscopic management of pancreatic pseudocyst/walled-off pancreatic necrosis (WOPN) without necrosectomy.

Methods: One-hundred and sixty-five pancreatic pseudocysts/WOPN managed endoscopically over a period of 22 years were analyzed retrospectively for technical success, complications, and recurrence.

Results: Symptomatic 118 males and 47 females with mean age of 35.

Pancreato-biliary Endoscopic Ultrasound in Opium Addicts Presenting with Abdominal Pain.

Objective: Asymptomatic dilatation of bile duct and symptomatic sphincter of Oddi dysfunction have been reported in opium addicts. Except one case report, there is no report in the literature on endoscopic ultrasound (EUS) study of pancreato-biliary system in opium addicts. The aim of the present study was to report the EUS features of pancreato-biliary system in opium addicts presenting with abdominal pain.

Short-term biliary stenting before mechanical lithotripsy for difficult bile duct stones.

Background And Study Aim: Short-term common bile duct stenting has been shown to decrease stone size, but its effect on mechanical lithotripsy has not been reported.

Patients And Methods: Sixty patients of difficult bile duct stones were subjected to mechanical lithotripsy. Thirty patients were subjected to mechanical lithotripsy at the time of first endoscopic retrograde cholangiopancreatography (group A) while another 30 patients were subjected to mechanical lithotripsy using trapezoid basket after a short period of stenting (group B).

Mediastinal paraganglioma: specific endoscopic ultrasound features.

Endoscopic ultrasound (EUS) features of mediastinal paraganglioma have not been described. In this paper, we report a female patient presented with cough and chest pain without any neuroendocrinal symptoms. Final diagnosis of mediastinal paraganglioma was made on thoracoscopic biopsy and immunohistochemistry after EUS-guided fine needle aspiration.