The goal of this study was to isolate cancer stem-like cells marked by high expression of CD44, a putative cancer stem cell marker, from primary oral squamous cell carcinomas and identify distinctive gene expression patterns in these cells. From 1 October 2013 to 4 September 2015, 76 stage III-IV primary oral squamous cell carcinoma of the gingivobuccal sulcus were resected. In all, 13 tumours were analysed by immunohistochemistry to visualise CD44-expressing cells.
View Article and Find Full Text PDFSuture granulomas result from the use of nonabsorbable suture and is an infrequent complication following thyroidectomy. When they occur, suture granulomas may mimic both benign and malignant diagnoses, posing a potential diagnostic challenge. Ultrasound-guided fine needle aspiration cytology is an accurate diagnostic modality for the workup of nodules within the thyroidectomy bed.
View Article and Find Full Text PDFHerbal remedies are increasingly being recognised in recent years as alternative medicine for a number of diseases including cancer. Curcuma longa L., commonly known as turmeric is used as a culinary spice in India and in many Asian countries has been attributed to lower incidences of gastrointestinal cancers.
View Article and Find Full Text PDFGonadotropin releasing hormone (GnRH) is a neuroendocrine decapeptide found in all vertebrate animals. The best understood function of GnRH is its endocrine function as a releasing hormone acting on the pituitary. But GnRH also functions as a neuromodulator within the nervous system.
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