Publications by authors named "Ashok Dalal"
Introduction: We aimed at evaluating the safety and efficacy of self-expandable metallic stent (SEMS) insertion for managing patients with benign gastric outlet obstruction (GOO).
Methods: This prospective interventional study included 23 patients. All consecutive treatment-naïve symptomatic patients with benign GOO were recruited.
Background And Aim: We aimed to study the etiologies and clinical profile and to describe the factors associated with mortality in acute-on-chronic liver failure (ACLF) patients at our center.
Methods: Patients meeting the Asian Pacific Association for the Study of the Liver (APASL) definition of ACLF were included. We studied etiologies and clinical profile and analyzed the factors associated with mortality in patients with ACLF.
Introduction Wire-guided bougienage of the upper esophageal sphincter (UES) was performed routinely before per-oral motorized power spiral enteroscopy (MSE). In the present study, we aimed to answer the clinical question of whether routine bougienage of UES is required. Methods This was a retrospective study that included 20 patients who underwent antegrade spiral enteroscopy for various indications.
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- The study aimed to compare the incidence of myelosuppression in patients starting azathioprine (AZA) at a full dose versus a gradual increase in dosage.
- Forty patients with inflammatory bowel disease were divided into two groups: one starting at 2 mg/kg (full dose) and the other beginning at 1 mg/kg with increases over time.
- Results showed similar rates of myelosuppression and relapses between the groups, although the full-dose group had slightly fewer relapses during follow-up.
Background And Aim: Minimal hepatic encephalopathy (MHE) reflects cognitive impairment in patients with liver cirrhosis and is associated with poor prognosis. We assessed the effects of nutritional therapy on cognitive functions, health-related quality of life (HRQOL), anthropometry, endotoxins, and inflammatory markers in cirrhotic patients with MHE.
Methods: In a double-blind randomized controlled trial, cirrhotic patients with MHE were randomized to nutritional therapy (group I: 30-35 kcal/kg/day and 1.
Article Synopsis
- The study investigates the effectiveness of urine neutrophil gelatinase-associated lipocalin (UNGAL) and renal resistive index (RRI) in diagnosing types of acute kidney injury (AKI) in patients with decompensated cirrhosis (DC).
- Researchers evaluated 86 DC patients with AKI over a year and measured UNGAL and RRI at diagnosis and after 48 hours.
- UNGAL showed excellent diagnostic accuracy (AUROC of 0.97) for differentiating acute tubular necrosis (ATN) from non-ATN AKI, while RRI had lower accuracy (AUROC of 0.68 initially and improved to 0.74 after 48 hours).
Background The European organization Research and Treatment of Cancer Quality of Life Questionnaire-Oesophagogastric 25 (EORTC QLQ-OG 25) is designed for patients with esophagogastric cancer. Its performance has never been tested with benign disorders. A health-related quality-of-life questionnaire does not exist for patients with benign corrosive-induced esophageal strictures.
View Article and Find Full Text PDFParaneoplastic pseudoachalasia: A rare manifestation of Hodgkin's lymphoma.
Indian J Gastroenterol
December 2023
Background and objectives Studies on the natural history of asymptomatic walled-off necrosis (WON) in acute pancreatitis (AP) are scarce. We conducted a prospective observational study to look for the incidence of infection in WON. Material and methods In this study, we included 30 consecutive AP patients with asymptomatic WON.
View Article and Find Full Text PDFBackground And Aim: Overt hepatic encephalopathy (OHE) has high risk of recurrence and is associated with poor survival. The role of nutrition therapy is well documented in cirrhosis, but its efficacy in preventing the recurrence of OHE has not been studied.
Methods: In double blind RCT, we randomly assigned 150 patients with liver cirrhosis, with history of OHE in recent past to receive nutrition therapy (group I) or no nutrition therapy (group II) and followed up for 6 months.
Introduction: The assessment of liver fibrosis is important in patients with chronic hepatitis C (CHC). In recent years, non-invasive tests like enhanced liver fibrosis (ELF) have been developed as an alternative to liver biopsy for estimating the severity of liver fibrosis. Therefore, we aimed to assess whether the ELF score can be used for fibrosis severity estimation using liver biopsy as the gold standard.
View Article and Find Full Text PDFBackground/aims: Response to vaccine in patients with inflammatory bowel disease is lower than in the general population. We aimed to evaluate the efficacy of hepatitis B virus (HBV) vaccination in patients with ulcerative colitis (UC) versus controls.
Methods: We prospectively compared antibody response to HBV vaccination in 100 patients with UC versus controls.