A Recent Update on the Role of Estrogen and Progesterone in Alzheimer's Disease.

Alzheimer's disease (AD), one of the most prevalent neurodegenerative disease responsible for 60%-80% dementia cases globally. The disease is more prevalent among elder females. Female reproductive hormones are found to be essential for cellular activities in brain.

Enhanced SOC estimation of lithium ion batteries with RealTime data using machine learning algorithms.

Accurately estimating Battery State of Charge (SOC) is essential for safe and optimal electric vehicle operation. This paper presents a comparative assessment of multiple machine learning regression algorithms including Support Vector Machine, Neural Network, Ensemble Method, and Gaussian Process Regression for modelling the complex relationship between real-time driving data and battery SOC. The models are trained and tested on extensive field data collected from diverse drivers across varying conditions.

The ocean carbon sinks and climate change.

The oceans act as major carbon dioxide sinks, greatly influencing global climate. Knowing how these sinks evolve would advance our understanding of climate dynamics. We construct a conceptual box model for the oceans to predict the temporal and spatial evolution of CO2 of each ocean, and the time-evolution of their salinities.

Exploring the potential of third-generation microalgae bio-alcohol and biodiesel in arresting particulate smoke emissions and greenhouse gases using CART.

Due to the rise in vehicular emissions, the rapid deterioration of the atmospheric air quality is a cause for concern in a global scale. In this context, the objective of this study is to explore the effect of post-injection parameters on a continuous active regeneration trap (CART) to mitigate harmful greenhouse gases (GHG) and particulate smoke emissions (PSE) using diesel fuel reformulated by long-chain microalgae bio-alcohol and low-density microalgae biodiesel. Furthermore, the efficiency of the CART unit is analyzed based on its ability to mitigate the harmful emissions without sacrificing the engine performance characteristics.

An overview on microalgae as renewable resources for meeting sustainable development goals.

The increased demands and dependence on depleted oil reserves, accompanied by global warming and climate change have driven the world to explore and develop new strategies for global sustainable development. Among sustainable biomass sources, microalgae represent a promising alternative to fossil fuel and can contribute to the achievement of important Sustainable Development Goals (SDGs). This article has reviewed the various applications of microalgal biomass that includes (i) the use in aquaculture and its sustainability; (ii) commercial value and emerging extraction strategies of carotenoids; (iii) biofuels from microalgae and their application in internal combustion engines; (iv) the use and reuse of water in microalgae cultivation; and (v) microalgae biotechnology as a key factor to assist SDGs.

Mucormycosis of the Breast in a Patient With Breast Carcinoma After COVID-19 Pneumonia.

Mucormycosis is a rare, but potentially fatal, fungal infection which is caused by mucormyctes. These forms of fungi are typically known to infect immuno-compromised individuals but are rare in immunocompetent individuals. Herein, we report the case of a 52 year-old female who was diagnosed with right breast carcinoma in Manipal Hospital, a tertiary cancer care center.

An Overview of the Impact of Body Mass Index on Pathological Complete Response Following Neoadjuvant Chemotherapy in Operable Breast Cancer in a Tertiary Care Centre in South India.

Objective: The incidence of female breast cancer in the world is 11.7% with a mortality rate of 6.9%.

Neurotic personality trait as a predictor in the prognosis of composite restorations: A 24-month clinical follow up study.

The role of personality traits in modulating the incidence and progression of medical disease conditions are well documented, however, there is a paucity of information for its effects on dental health conditions and specifically on the prognosis of restorative dental materials. This study aims to evaluate the clinical performance of Micro-hybrid and Nano-ceramic composite restorations among patients with different personality traits. A total of 323 patients, indicated to receive operative treatment at a University Dental College Hospital, were invited to participate in this study.

Lipid- and Polymer-Based Nanoparticle Systems for the Delivery of CRISPR/Cas9.

The discovery of clustered regularly interspaced short palindromic repeat (CRISPR)/ CRISPR-associated (Cas) genome editing systems and their applications in human health and medicine has heralded a new era of biotechnology. However, the delivery of CRISPR therapeutics is arguably the most difficult barrier to overcome for translation to clinical administration. Appropriate delivery methods are required to efficiently and selectively transport all gene editing components to specific target cells and tissues of interest, while minimizing off-target effects.

State of art of valorising of diverse potential feedstocks for the production of alcohols and ethers: Current changes and perspectives.

Alcohols could be the biggest factor for the improvement of world biofuel economy in the present century due to their excellent properties compared to petroleum products. The primary concerns of sustainable alcohol production for meeting the growing energy demand owing to the selection of viable feedstock and this might enhance the opportunities for developing numerous advanced techniques. In this review, the valorization of alcohol production from several production routes has been exposed by covering the traditional routes to the present state of the art technologies.

Insight into the recent advances of microwave pretreatment technologies for the conversion of lignocellulosic biomass into sustainable biofuel.

The utilization of renewable lignocellulosic biomasses for bioenergy synthesis is believed to facilitate competitive commercialization and realize affordable clean energy sources in the future. Among the pathways for biomass pretreatment methods that enhance the efficiency of the whole biofuel production process, the combined microwave irradiation and physicochemical approach is found to provide many economic and environmental benefits. Several studies on microwave-based pretreatment technologies for biomass conversion have been conducted in recent years.

Influence of personality traits on the intensity of maximum voluntary bite force in adults.

Purpose: To determine the Maximum voluntary bite force among patients having different personality traits.

Methods: In total, 323 patients were given the big-five inventory (BFI) questionnaire to fill and allotted to the various personality traits. The patients in the Agreeableness (n = 62) and Neuroticism traits (n = 62) were included in the study.

Influence of Neuroticism on the Prognosis of Nanoceramic and Microhybrid Composite Restoration: A Comparative 1-year Clinical Study.

Aim: This study aimed to compare the clinical performance of nanoceramic and microhybrid-based composite restorations in adult patients with different personality traits.

Materials And Methods: Patients in accordance with the inclusion and exclusion criteria were asked to complete the BFI (Big Five Inventory) questionnaire. Of a total of 323 patients, 124 (67 males and 57 females) patients were categorized into agreeableness and neuroticism traits and were included in the study.

Effect of diethyl ether and ethanol as an oxygenated additive on Calophyllum inophyllum biodiesel in CI engine.

The present experimental investigation is conducted to examine the working characteristics of compression ignition (CI) engine using oxygenated additives such as diethyl ether and ethanol to the blends of Calophyllum inophyllum biodiesel. Experiments are conducted on a water-cooled single-cylinder constant speed DI (direct injection) diesel engine under same operating circumstances. The results indicates that an enhancement of brake thermal efficiency is up to 3.

CRISPR/Cas systems to overcome challenges in developing the next generation of T cells for cancer therapy.

Genetically engineered immune cells with chimeric antigen receptors (CAR) or modified T cell receptors (TCR) have demonstrated their potential as a potent class of new cancer therapeutic strategy. Despite the clinical success of autologous CD19 CAR T cells in hematological malignancies, allogeneic T cells exhibit many advantages over their autologous counterparts and have recently gathered widespread attention due to the emergence of multiplex genome editing techniques, particularly CRISPR/Cas systems. Furthermore, genetically engineered T cells face a host of major challenges in solid tumors that are not as significant for blood cancers such as T cell targeted delivery, target specificity, proliferation, persistence, and the immunosuppressive tumor microenvironment.

Biodegradable and non-biodegradable fraction of municipal solid waste for multifaceted applications through a closed loop integrated refinery platform: Paving a path towards circular economy.

An increase in population, rapid urbanization and industrialization has accelerated the rate of municipal solid waste generation. The current disposal of solid waste is a burgeoning issue and it's in immediate need to shift the existing disposal processes to a sustainable manner. Circular economy (CE) is a conceptual model which is been used for better use of resources and minimization of waste in a closed loop approach which could be appropriate for waste management.

Prevention of glucose-induced cataract by prepared by (paste of Linn).

Background: Cataract is a major cause of blindness worldwide. Researchers received much attention from the traditional systems such as Ayurveda for the solutions of cataract through antioxidant activities apart from the surgical extraction.

Aims: A To study, the anti-cataract activity of (VK) prepared with ( Linn) (paste) in (fat) of the domestic fowl () on glucose-induced cataract in ovine (sheep) lenses.

Comparison of bite force on the dominant and nondominant sides of patients with habitual unilateral chewing: a pilot study.

Occlusion and chewing-side preference (CSP) are complex aspects of the stomatognathic system. The present study aimed to record the difference in bite force between the dominant and nondominant chewing sides of patients with a CSP. A sample of 95 subjects (aged 20-35 years) with established CSPs was selected.

Electrospinning of polyvinyl alcohol into crosslinked nanofibers: An approach to fabricate functional adsorbent for heavy metals.

Electrospun nanofibers have a wide range of applications due to their unique miniature size and accompanying ultra-high specific surface area. Polyvinyl alcohol(PVA) is a kind of hydrophilic materials, and hence its nanofiber morphology prepared by electrospinning disappeared after solution immersing. In the present work, crosslinked PVA nanofibers were prepared by electrospinning and then employing glutaraldehyde vapor crosslinking to improve their water resistance and mechanical properties.

Extended adipofascial wrap around radial forearm flap for hard palate reconstruction.

Background: While using radial forearm free flap in palate reconstruction, the pedicle lies in the nasal floor, constantly exposed to the nasal secretions and turbulent air current. To overcome this problem, we have designed a procedure which utilises the adipofascial extension to wrap the pedicle and nasal side of the flap.

Materials And Methods: The study was done during 2017 and 2018, 2 years' period.

Effect of "DXB-2030," a Polyherbal Formulation, on Experimental Polycystic Ovary Syndrome Associated with Hyperandrogenism.

The objective of the present study was to evaluate "DXB-2030," a polyherbal combination of , , , , and extracts in an experimental model of testosterone propionate (TP), induced polycystic ovary syndrome (PCOS) in female rats. Thirty animals were divided into 3 groups of 10 each; group 1 served as normal control; group 2 was administered with TP and served as positive control; along with TP, group 3 was treated with "DXB-2030" at a dose of 100 mg/kg p.o.

Preparation and properties of cellulose/Thespesia lampas microfiber composite films.

The fibers from the newly identified plant Thespesia lampas (TL) were converted into microfibers in order to increase their aspect ratio. The TL microfibers (TLMFs) were used as reinforcement (1 wt. to 5 wt%) in cellulose matrix to prepare cellulose /TLMFs composite films.

Infrared and Raman spectroscopic studies of Mn ions doped in strontium alumino borate glasses: Describes the role of AlO.

Strontium alumino borate glasses doped with Mn ions (SABM) have been prepared and characterized by XRD, density, Electron paramagnetic resonance (EPR), FT-IR and Raman to investigate the spectral and physical properties of the present glass samples. The FTIR spectra revealed the presence of BO and BO structural units in SABM glasses. The IR peak at ~467 and ~679 cm assigned as the vibration of metal cations (Sr), MnO bond vibrations and bending vibration of AlO in [AlO] units.

A Revisit to High Jugular Bulb: A Newer Clinical Grading.

A revisit to high riding jugular bulb with a newer classification. Observational study. Patients in the age group between 15 to 60 years, who underwent various Tympanomastoid and otosclerotic surgeries from April 2015 to 2018, have been included in the study.