A male river otter from Georgia exhibited lethargy, appetite loss, and severe anemia, later diagnosed with intraerythrocytic piroplasms before dying three days after being presented at a rehabilitation center.
Necropsy revealed yellowing of fatty tissues and liver, accompanied by liver cell degeneration linked to hypoxia from hemolytic anemia, with piroplasms found in red blood cells.
Genetic testing of otters across several eastern U.S. states and California showed a significant prevalence of Babesia sp., with consistent gene sequences indicating a common piroplasm type affecting otters in the region.