Publications by authors named "Ashley Yoo"
Automated Intraoperative Visual Detection of Pediatric Epileptogenic Brain Lesions Using a Machine Learning Classifier.
Annu Int Conf IEEE Eng Med Biol Soc
July 2024
450,000 children with epilepsy in the United States suffer lifelong disability and are at risk of sudden death. Surgical treatment of epilepsy is limited by the ability to visually discriminate between normal and abnormal brain tissue using visual light surgical microscopes: resection of excessive tissue can lead to neurologic injury, while insufficient resection often does not lead to durable cures. We propose a machine-learning-based segmentation model to identify epileptogenic, abnormal tissue thereby improving accuracy of surgical resection.
View Article and Find Full Text PDFBackground And Aims: The presence of steatosis in a donor liver and its relation to post-transplantation outcomes are not well defined. This study evaluates the effect of the presence and severity of micro- and macro-steatosis of a donor graft on post-transplantation outcomes.
Methods: The UNOS-STAR registry (2005-2019) was used to select patients who received a liver transplant graft with hepatic steatosis.
Background & Aims: In this study, we evaluate the effects of donor gender on post-liver transplant (LT) prognosis. We specifically consider patients with primary biliary cholangitis (PBC).
Methods: The 2005 to 2019 UNOS transplant registry was used to select patients with PBC.
Article Synopsis
- Pancreas transplantation can help diabetes patients achieve better glucose control, but current rejection monitoring methods like blood tests and biopsies are not very effective.
- A study involving 181 dd-cfDNA samples from 77 patients showed that dd-cfDNA levels were generally low (<1.0%) post-transplant, but increased during rejection or infection episodes.
- The findings suggest that dd-cfDNA could be a useful biomarker for detecting issues in pancreas transplants, as its levels correlate with transplant dysfunction.
Background And Aims: Hepatitis C virus (HCV) is a prominent liver disease that often presents with mental illness. We stratify the HCV population and review its healthcare burden on the US hospital system.
Methods: The US National Inpatient Sample was used to select admissions related to HCV between 2016 and 2019.
The Src family kinases (SFK) are homologs of retroviral oncogenes, earning them the label of proto-oncogenes. Their functions are influenced by positive and negative regulatory tyrosine phosphorylation events and inhibitory and activating intramolecular and extramolecular interactions. This regulation is disrupted in their viral oncogene counterparts.
View Article and Find Full Text PDFArticle Synopsis
- Prediabetes is a precursor to type 2 diabetes, and its risks can be mitigated through physical activity, a healthy diet, and weight loss, with mHealth technology like the Sweetch app providing a viable solution for managing these factors.
- A pilot study evaluated the Sweetch app and a digital body weight scale over three months, focusing on feasibility (retention rates), acceptability (user satisfaction), and effectiveness (changes in physical activity, weight, and blood metrics).
- Results showed high retention (86%), strong user satisfaction (76-93% scores), increased physical activity (2.8 MET-hours/week), and significant weight loss (1.6 kg), alongside improvements in glycated hemoglobin, indicating promising