A randomized controlled trial of analgesia during vaccination in adults.

Although immunization injections are the most common painful medical procedures, pain-relieving interventions are not routinely used. In this randomized controlled trial, we compared the effectiveness of topical anesthesia using liposomal lidocaine to: (1) vapocoolant spray using a proprietary blend of 1,1,1,3,3-pentafluoropropane and 1,1,1,2-tetrafluoroethane; (2) nurse-administered tactile stimulation; or (3) self-directed distraction by means of reading a magazine. Liposomal lidocaine was more effective (p View Article and Find Full Text PDF

Comparison of pain during two methods of urine collection in preterm infants.

Background: Suprapubic aspiration (SPA) and urine catheterization (UC) are performed frequently in preterm neonates to rule out urinary tract infection; however, a comparison of the pain caused by both procedures has not been made previously.

Objective: To compare pain responses in preterm infants who are undergoing urine collection by using SPA versus UC.

Methods: Prospective, single-blind, randomized clinical trial was conducted in 2 NICUs.

Variability in clinical practice guidelines for sweetening agents in newborn infants undergoing painful procedures.

Objective: Sweetening agents have been recommended in position statements and consensus documents for procedural pain management in neonates; however, it is not clear if this has resulted in widespread adoption in clinical practice. The objective of this study was to investigate unit-specific protocols for the use of sweetening agents.

Methods: Structured telephone survey with qualified personnel in special care (level II) nurseries and neonatal intensive care (level III) units across Canada.