Artificial intelligence in clinical and translational science: Successes, challenges and opportunities.

Artificial intelligence (AI) is transforming many domains, including finance, agriculture, defense, and biomedicine. In this paper, we focus on the role of AI in clinical and translational research (CTR), including preclinical research (T1), clinical research (T2), clinical implementation (T3), and public (or population) health (T4). Given the rapid evolution of AI in CTR, we present three complementary perspectives: (1) scoping literature review, (2) survey, and (3) analysis of federally funded projects.

Severe ectopic Cushing's syndrome.

We present a rare case of severe ectopic Cushing's syndrome in a 39-year-old woman with a rapid onset of signs and symptoms and severe hypokalemia. Further workup demonstrated an adrenocorticotropic hormone-secreting metastatic high-grade neuroendocrine carcinoma.