Publications by authors named "Ashley Tang"

Article Synopsis
  • - The presence of tumor-associated macrophages (TAMΦs) in triple-negative breast cancer (TNBC) is linked to worse patient outcomes, leading to efforts to stop their infiltration.
  • - Researchers found that not just chemotaxis, but also random migration significantly contributes to macrophage infiltration in tumors, with tumor-associated monocytes (TAMos) showing enhanced movement abilities.
  • - IL-6, released by both cancer cells and TAMos, boosts the migration of TAMos and their ability to promote cancer cell growth, suggesting that targeting IL-6 could improve therapies aimed at managing TAMΦ infiltration.
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Background: Spinal metastases are commonly seen in patients with cancer and often indicate a poor prognosis. Treatment can include curative or palliative surgery, chemotherapy, and radiation therapy. The surgical approach varies widely on the basis of the affected region of the spine, the location of the tumor (anterior versus posterior), the goal of surgery, the health of the patient, and surgeon preference.

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The purpose of this narrative review is to elucidate the ways the clinicians working on forensic medical evaluations can engage with asylum proceedings. We compare the legal and medical perspectives on different aspects of forensic medical evidence, asylum evaluations, and asylum applications. As asylum seekers must demonstrate a well-founded fear of persecution in order to receive asylee status, legal and medical professionals often need to collaborate in asylum cases.

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Primary care physicians (PCPs) have an important role in the identification and management of Attention Deficit Hyperactivity Disorder (ADHD). There is a paucity of research on PCPs' practices related to the discussion of educational interventions. We conducted a retrospective chart review using Natural Language Processing to extract data on how often PCPs in an outpatient clinic: 1) discuss educational support with patients and caregivers; and 2) obtain educational records.

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Article Synopsis
  • Estrogen receptor-positive breast tumors often respond to endocrine therapy but can develop resistance due to genetic changes, particularly in the estrogen receptor alpha (ESR1).
  • A study found that the incidence of new (de novo) ESR1 mutations in treatment-naïve primary breast tumors is much lower compared to metastatic tumors and previously treated tumors, suggesting these mutations are not common at the initial stage.
  • The findings indicate that pathogenic ESR1 mutations typically relate to acquired resistance rather than an intrinsic resistance mechanism, implying universal testing of primary breast cancer for ESR1 mutations may not be necessary.
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spp. and () are two of the deadliest foodborne pathogens in the US. Genes involved in antimicrobial resistance, virulence, and stress response, enable these pathogens to increase their pathogenicity.

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