Publications by authors named "Ashley McWilliams"

Article Synopsis
  • Atopic dermatitis (AD) is a chronic skin condition that often begins in childhood and can lead to other health issues, with dupilumab being the first biologic treatment approved for moderate to severe cases in adults and adolescents.
  • A study reviewed the off-label use of dupilumab in children, showing that 89.5% of patients accessed the medication after about 9 weeks, with varying dosing guidelines based on age.
  • The findings indicated that children generally tolerated dupilumab well, but optimal dosing for those under 12 years is still unclear, and the study faced limitations in data collection due to its retrospective nature.
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Acquired perforating dermatosis (APD) is characterized by pruritic craterlike lesions with a predilection for patients affected by chronic kidney disease or diabetes mellitus (DM). We present a case of a 57-year-old black woman admitted for chest pain and dyspnea who was found to have 2 teardrop-shaped yellow-white-chalky plaques consistent with APD that developed at the site of a preexisting split-thickness skin graft (STSG). We also review the literature on APD.

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Otophyma is a rare condition characterized by edematous deformation of the ear that is considered to be the end-stage of an inflammatory process such as rosacea and eczema. This report illustrates a case in an elderly male, originally thought to have leprosy. Biopsy revealed a nodular infiltration of inflammatory cells around adnexal structures and an intraepidermal cyst.

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