Publications by authors named "Ashley Marumoto"
Enormous Gallstone Discovered in the Setting of Acute-on-chronic Cholecystitis.
Hawaii J Health Soc Welf
November 2021
Biliary disease is a common surgical problem. A unique case of a 53-year-old male with an enormous gallstone precluding safe laparoscopic cholecystectomy is presented. The patient was a 53-year-old male who presented to the emergency department with a 1-day history of abdominal pain for which clinical findings were consistent with acute cholecystitis.
View Article and Find Full Text PDFArticle Synopsis
- Phyllodes tumors (PT) are rare tumors classified as benign, borderline, or malignant, with the study involving 76 patients diagnosed between 2009 and 2019.
- Among the patients, 61.8% had benign PT, 11.8% had borderline, and 26.3% had malignant, with a mean age of 52 at diagnosis.
- Surgical treatments varied: benign PT often received excisional biopsy, while malignant PT frequently underwent lumpectomy or mastectomy; recurrence rates were low, but positive margins were linked to higher recurrence.
Article Synopsis
- The study evaluates national compliance with the Cancer Program Practice Profile Reports (CP3R) metrics, focusing on the use of combination chemotherapy or chemo-immunotherapy for certain breast cancer patients within 120 days of diagnosis.
- An analysis of data from the National Cancer Database shows an increase in treatment concordance from 75.7% in 2004 to 89.5% in 2014, with better overall survival for patients receiving recommended treatments.
- Patients treated at academic hospitals and those with private insurance experienced greater survival benefits, highlighting the importance of accessibility to high-quality care.
Article Synopsis
- Fibroepithelial lesions of the breast (FEL) include a range of tumors such as fibroadenomas and phyllodes tumors, which can be challenging to distinguish in core needle biopsies.
- A study of 305 patients from 2009 to 2019 found that 25.8% of cases upgraded to phyllodes tumors after excision, with factors like age over 50, larger size, and specific histological features increasing upgrade risk.
- The results suggest excising FEL is generally recommended, but monitoring smaller tumors may be a safe option for some patients.
For women with breast cancer in whom multiple Oncotype DX Recurrence Scores (RS) are obtained, RS concordance utilizing current NCCN recommendations has not been evaluated. Patients with two or more RS were identified. RS were stratified by NCCN guidelines and compared for concordance.
View Article and Find Full Text PDFA cross-sectional study of breast pain in a diverse population of breast cancer patients.
J Psychosoc Oncol Res Pract
January 2021
Background: Breast cancer is the most common cancer in women, and postoperative breast pain has been reported to be anywhere from 25% to 60%. However, there is sparse data regarding racial/ethnic differences in breast pain among breast cancer patients.
Methods: We performed a cross-sectional anonymous survey of breast cancer patients from the Hawaii Cancer Consortium over a 6-week period between 2019 and 2020.
An Uncommon Pairing of common Tumors: Case Report of Ductal Carcinoma Within Fibroadenoma.
Hawaii J Med Public Health
February 2019
Fibroadenomas are common benign tumors of the female breast. In the appropriate clinical setting, they are often managed expectantly without excision. Rarely, cancer may arise within a fibroadenoma, and this diagnosis mandates prompt treatment for malignancy.
View Article and Find Full Text PDFBackground: Abdominal surgery in critically ill patients has high mortality, contributing to high US healthcare costs. This study sought to identify specific predictors of mortality in this population.
Methods: Using the National Surgical Quality Improvement Program database 2006 to 2012, we identified 4,901 patients who were intubated for more than 48 hours before undergoing common abdominal procedures.
Trial and error: investigational drug induced liver injury, a case series report.
Hawaii J Med Public Health
September 2013
This is a case report series of four patients who exhibited signs and symptoms of acute liver dysfunction during participation in a Phase I trial of a novel non-steroidal anti-inflammatory drug (NSAID) designed to inhibit microsomal prostaglandin synthase 1 (MPGES1). Within one month of trial initiation, all four patients presented with epigastric pain, fatigue, nausea, and increasing liver function tests (LFTs). Two out of four patients required hospitalization, underwent liver biopsies, and were treated with N-acetylcysteine.
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