Publications by authors named "Ashley M Guerrero"
Article Synopsis
- The study aims to identify host anti-viral factors that can help control SARS-CoV-2 infection, which have been overlooked in previous research focused mainly on pro-viral factors.*
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- Using a genome-wide CRISPR dropout screen, the researchers found several underappreciated host factors, such as components of V-ATPases, ESCRT, and N-glycosylation pathways, which affect viral entry and replication.*
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- Key findings include the identification of the cohesin complex as an anti-viral pathway and the transcription factor KLF5, which is linked to severe COVID-19 symptoms, shedding light on the genetic and molecular interactions that influence the severity of the disease.*
