Publications by authors named "Ashley Lester"
Article Synopsis
- * Researchers analyzed 1,294 mesothelioma samples through advanced sequencing techniques and found notable differences in mutational patterns and PD-L1 expression between the more common epithelioid type and the less common nonepithelioid type.
- * The findings reveal that mesothelioma largely features inactivating mutations in key tumor suppressor genes, and emphasize the need for new treatment methods targeting these specific genetic alterations due to the limited effectiveness of existing therapies.
We assess quantitatively the effect of exogenous health improvements on output per capita. Our simulation model allows for a direct effect of health on worker productivity, as well as indirect effects that run through schooling, the size and age-structure of the population, capital accumulation, and crowding of fixed natural resources. The model is parameterized using a combination of microeconomic estimates, data on demographics, disease burdens, and natural resource income in developing countries, and standard components of quantitative macroeconomic theory.
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