Significant life events and their impact on alcohol and drug use: a qualitative study.

This study used a life-course perspective to identify and understand life events related to long-term alcohol and other drug (AOD) use trajectories across the life span. Using a purposive sample, we conducted semi-structured telephone interviews with 48 participants (n = 30 abstinent and 18 non-abstinent) from a longitudinal study of AOD outcomes 15 years following outpatient AOD treatment. A content analysis was conducted using ATLAS.

Mechanisms underlying epigenetic regulation in Arabidopsis thaliana.

In plants, epigenetic regulation mediates both the proper development of the plant and responses to environmental cues. Changes in epigenetic states employ DNA methylation, histone modification, and regulatory RNAs. In Arabidopsis thaliana, DNA methylation as a repressive mark is often associated with constitutively silenced loci, such as repetitive sequences, transposons, and heterochromatin.

Novel functional roles for PERIANTHIA and SEUSS during floral organ identity specification, floral meristem termination, and gynoecial development.

The gynoecium is the female reproductive structure of angiosperm flowers. In Arabidopsis thaliana the gynoecium is composed of two carpels that are fused into a tube-like structure. As the gynoecial primordium arises from the floral meristem, a specialized meristematic structure, the carpel margin meristem (CMM), develops from portions of the medial gynoecial domain.