Autoimmune Heparin-Induced Thrombocytopenia: A Diagnostic and Management Challenge After Transcatheter Aortic Valve Replacement.

Heparin-induced thrombocytopenia (HIT) is a commonly encountered condition, especially in inpatient settings, and is often attributed to high mortality and prolonged hospital stays. A rare entity, autoimmune heparin-induced thrombocytopenia (aHIT) refers to a condition in which antiplatelet factor-4 (PF4) antibodies activate platelets even in the absence of heparin. Our patient presented 12 days after transcatheter aortic valve replacement (TAVR) with altered mental status and severe thrombocytopenia.

Immune thrombocytopenia in a 68-year-old woman after COVID-19 vaccination.

This case discusses a patient who presented with immune thrombocytopenia purpura (ITP) one week after COVID-19 vaccination, introducing ITP as a consideration for a potential, but rare, adverse reaction to COVID-19 vaccination.