Publications by authors named "Ashley J Kang"
Higher-Order Disease Interactions in Multimorbidity Measurement: Marginal Benefit Over Additive Disease Summation.
J Gerontol A Biol Sci Med Sci
December 2024
Background: Current multimorbidity measures often oversimplify complex disease interactions by assuming a merely additive impact of diseases on health outcomes. This oversimplification neglects clinical observations that certain disease combinations can exhibit synergistic effects. Thus, we aimed to incorporate simultaneous higher-order disease interactions into the validated ICD-coded multimorbidity-weighted index, to assess for model improvement.
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- The study aimed to map conditions from a multimorbidity-weighted index (MWI) to ICD-10 codes, creating a new MWI-ICD10 and updating MWI-ICD9 for consistency assessment.
- Conducted at a large medical center from 2013 to 2017, the research involved adults aged 18 and older, analyzing their health encounters over a four-year period.
- Results showed that MWI-ICD10 closely mirrored the prevalence of chronic conditions found in MWI-ICD9, with minimal differences during the transition from ICD-9 to ICD-10, suggesting this new index effectively measures multimorbidity in health records.
Fabricated ecosystems (EcoFABs) offer an innovative approach to in situ examination of microbial establishment patterns around plant roots using nondestructive, high-resolution microscopy. Previously high-resolution imaging was challenging because the roots were not constrained to a fixed distance from the objective. Here, we describe a new 'Imaging EcoFAB' and the use of this device to image the entire root system of growing at high resolutions (20×, 40×) over a 3-week period.
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