Publications by authors named "Ashley C Wynne"
Article Synopsis
- Asthma causes inflammation and mucus buildup in the lungs, impacting airflow and making it difficult for orally or inhaled drugs to work effectively.
- This study tested the diffusion of two asthma medications, theophylline and albuterol, through an artificial mucus layer, measuring their concentration over time using special spectroscopy techniques.
- The results yielded diffusion coefficients for the drugs, which matched previous studies, and demonstrated a novel, non-invasive method to evaluate how well drugs can penetrate through complex mucus conditions.
