Effects of stannous fluoride dentifrice on gingival health and oxidative stress markers: a prospective clinical trial.

Background: Periodontal disease results in oral dysbiosis, increasing plaque virulence and oxidative stress. Stannous fluoride (SnF) binds lipopolysaccharides to reduce plaque virulence. This study prospectively assessed SnF effects on oxidative stress in adults with gingivitis.