Fibrous incudostapedial joint in congenital aural atresia.

Objectives: (1) Determine the prevalence of a non-bony or fibrous incudostapedial (IS) joint in the setting of congenital aural atresia. (2) Assess this anomaly's impact on surgical management and associated hearing outcomes.

Study Design: Retrospective chart review.

HEAR MAPS a classification for congenital microtia/atresia based on the evaluation of 742 patients.

Objective: Describe anatomical and radiological findings in 742 patients evaluated for congenital aural atresia and microtia by a multidisciplinary team. Develop a new classification method to enhance multidisciplinary communication regarding patients with congenital aural atresia and microtia.

Methods: Retrospective chart review with descriptive analysis of findings arising from the evaluation of patients with congenital atresia and microtia between January 2008 and January 2012 at a multidisciplinary tertiary referral center.

Immunocytochemical localization of the translocase of the outer mitochondrial membrane (Tom20) in the human cochlea.

Mitochondrial degeneration in the inner ear is likely a contributing factor in age-related hearing loss and other otopathologies such as Meniere's disease. Most mitochondrial proteins are synthesized in the cytosol and imported through the mitochondrial membranes by translocators. The translocase of the outer membrane (Tom) is the universal entry gate for all proteins that are imported into mitochondria.

Cancer of unknown primary: does treatment modality make a difference?

Objectives/hypothesis: We systematically reviewed the published experience on the treatment outcomes of patients with head and neck cancer of unknown primary (CUP) to determine if treatment modality affects survival outcomes.

Study Design: Meta-analysis.

Methods: A comprehensive literature search was performed for articles reporting survival outcomes for CUP in the head and neck published within the last 12 years.

Temporal bone histopathology and immunoglobulin deposition in Sjogren's syndrome.

Hypothesis: The histopathology of Sjogren's syndrome (SS) in the human inner ear correlates with mouse models of autoimmune inner ear disease.

Background: SS is an autoimmune disease in which 25% of patients have sensorineural hearing loss (SNHL). The inner ear histology in a SS mouse model has shown degeneration of the stria vascularis (SV) and immunoglobulin G deposition on the basement membrane of SV blood vessels.

Evolution of sinonasal symptoms following endoscopic anterior skull base surgery.

Unlabelled: To assess the severity and evolution of sinonasal symptoms in patients following endoscopic anterior skull base surgery to define the typical postoperative course.

Design: Cross sectional study. Participants include 69 patients who underwent endoscopic skull base surgery by a dual surgeon team (otolaryngologist and neurosurgeon) from January 2008 to August 2009.

Magnetic resonance imaging findings in delayed facial palsy after stapes surgery.

Objectives: 1. To retrospectively review the pathophysiology and radiologic features of delayed facial palsy after stapedectomy. 2.