Publications by authors named "Ashlen Garrett"
Artif Organs
October 2023
Article Synopsis
- Extracorporeal life support (ECLS) is utilized for patients with severe cardiac and pulmonary failure, consisting mainly of cardiopulmonary bypass (CPB) and extracorporeal membrane oxygenation (ECMO), both of which come with risks of thrombus formation and bleeding.
- A study was conducted using ex vivo models of CPB and ECMO to assess the effects of nitric oxide (NO) as an alternative anticoagulant alongside heparin.
- Results indicated that NO alone was ineffective in preventing thrombus formation, but delivered in combination with low-level heparin showed some antiplatelet effects, though further investigation is needed to assess NO's anti-inflammatory benefits in ECMO systems.
