Publications by authors named "Ashleigh Crane"
Maternal ingestion of cannabidiol (CBD) in mice leads to sex-dependent changes in memory, anxiety, and metabolism in the adult offspring, and causes a decrease in survival to weaning age.
Martina Krakora Compagno Claudia Rose Silver Alexis Cox-Holmes Kari B Basso Caroline Bishop Ashleigh Crane
Pharmacol Biochem Behav
October 2024
Article Synopsis
- The study investigates the health, metabolic, and behavioral impacts of perinatal cannabidiol (CBD) exposure on female mice and their offspring into adulthood, highlighting the lack of research on this widely used supplement.
- Results indicate that maternal CBD exposure can negatively affect offspring survival and postnatal development, particularly in males, while also producing various sex-dependent metabolic and behavioral changes in adults.
- The findings suggest CBD exposure during pregnancy and lactation influences behaviors such as anxiety and obsessive-compulsive traits, with significant implications for understanding the safety and effects of CBD use during pregnancy.