Additivity of pilocarpine to bimatoprost in ocular hypertension and early glaucoma.

Purpose: To determine if the intraocular pressure (IOP) effect of pilocarpine at various concentrations is additive to that of bimatoprost and to assess the tolerability of this combination.

Methods: This was a randomized, prospective trial of patients with IOP > 21 mm Hg following appropriate medication washout. For all visits IOP was measured at 9:00 AM and 11:00 AM.

The effect of laser iridotomy on the anterior segment anatomy of patients with plateau iris configuration.

Purpose: To determine if laser iridotomy altered the anterior segment anatomy of patients with plateau iris configuration.

Methods: Twenty eyes of 9 female and 1 male patients were imaged using an ultrasound biomicroscope within 19 weeks before and 52 weeks after laser iridotomy. Measurements obtained included the anterior chamber depth (ACD), trabecular-ciliary process distance (TCPD), iris thickness (IT), angle opening distance at 500 micrometers (AOD), iridozonular distance (IZD), and trabecular-iris angle (TIA).