Publications by authors named "Ashish K Singh"

Class I bimaxillary protrusion is characterized by proclined incisors, a convex facial profile, procumbent lips, and increased lip strain. Treatment includes the extraction of premolars and the mesial movement of the proclined anterior teeth in the extraction spaces to correct the inclination. This case report describes the treatment of an 18-year-old male patient who presented with class I bimaxillary protrusion and procumbent lips.

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The class II bimaxillary protrusion malocclusion with class II or end on molar relation is generally associated with procumbency of lips. This case report presents a case of a 17-year-old nongrowing male patient with a traumatized left central incisor due to a fall with a chief complaint of forwardly placed and gap in upper front teeth. The traumatized left central incisor with Ellis class IV fracture was with a loss of crown structure and a poor prognosis of remaining tooth structure.

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Background and objective Alcoholic liver disease (ALD) encompasses a spectrum of liver conditions caused by excessive alcohol consumption, including fatty liver, alcoholic hepatitis, and cirrhosis. Both phenotypical and biochemical changes in gonadal hormones are observed across these stages. This study aimed to evaluate the clinical, biochemical, and hormonal abnormalities in patients with varying degrees of ALD and to assess their correlation with disease severity.

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Aim: This study aims to evaluate the efficacy of coated nanoparticles within orthodontic appliances as a novel strategy to enhance their antibacterial properties.

Material And Methods: A systematic search for relevant articles published between 2013 and March 2024 was conducted across electronic databases including PubMed, Scopus, Web of Science, and EBSCOhost. Studies meeting pre-defined eligibility criteria were included and assessed for methodological quality.

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To develop an artificial intelligence (AI)-based algorithm for the assessment and comparison of skeletal maturation in patients with and without cleft lip and/or palate and to detect the presence of cervical vertebral anomalies (CVAs). Retrospective cohort study. A university orthodontic clinic and comprehensive cleft care centers.

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Spring water is a vital drinking resource for residents in the Eastern Himalayas' Sikkim, India. While our initial investigations into spring water quality highlighted concerning levels of fecal coliform bacteria, the bacterial community composition (BCC) of these springs remains largely unexplored. This study sought to elucidate the BCC of Himalayan spring water, exploring its effects on water quality and delving into the unique bacterial ecology of these high-altitude springs.

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Class III malocclusion presents many challenges due to its varying elements of imbalance in skeletal, dental, and soft tissues. This necessitates a comprehensive treatment plan, including growth modification during the pre-pubertal growth phase, and long-term retention to reduce the chances of orthognathic surgery later. The components of Class III malocclusion include maxillary retrognathism, mandibular prognathism, or, in some cases, a combination of both.

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Objective: To evaluate and compare antimicrobial efficacy of Chlorhexidine and Chlorine dioxide mouthwashes on . biofilm created on metal and ceramic self-ligating brackets.

Materials And Methods: A total of 162 metal and ceramic self-ligating brackets (3M™ SmartClip™ & Clarity SL™) were randomly divided into 3 groups and 2 subgroups.

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Article Synopsis
  • Advances in orthodontics now allow adult patients with skeletal Class II malocclusion to benefit from non-surgical treatments using temporary anchorage devices (TADs), specifically maxillary molar distalization, instead of relying solely on surgery.
  • This case report details the treatment of a 50-year-old female with Class II malocclusion who utilized an infra-zygomatic crest (IZC) bone screw for effective tooth movement without unwanted side effects.
  • The use of bone screws enhances anchorage, minimizes reciprocal effects, and lessens the need for patient compliance, ultimately improving both dental alignment and facial aesthetics in adult orthodontic patients.
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This review aims to evaluate the current ethical dilemmas faced by healthcare practitioners, especially in dentistry, and analyze how conventionalism with ethical norms influences these challenges. By exploring the balance between evolving healthcare practices and established ethical principles, the review aims to provide insights into the ongoing ethical discussions and dilemmas within the field. A systematic search for relevant articles published between 2000 and July 2024 was conducted across various databases, including Web of Science, PubMed, Scopus, and EBSCO host.

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Transmigration of mandibular canine teeth is a rare dental anomaly characterized by the tooth's aberrant migration through the alveolar bone. This deviation from the expected eruption pathway can lead to tooth impaction, root resorption, periodontal problems, and aesthetic concerns. The exact cause of transmigration is not fully understood, but it is believed to be influenced by a combination of genetic, developmental, and environmental factors.

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Article Synopsis
  • A study was conducted to evaluate the treatment outcomes of single-dose liposomal amphotericin B for visceral leishmaniasis (VL) and post-kala-azar dermal leishmaniasis (PKDL), involving 527 cases, primarily VL.
  • The cure rate for VL was found to be 95%, with significant differences in treatment success between genders and age groups; males had higher success rates than females, while younger patients (≤23 years) also fared better.
  • The study highlighted that PKDL patients treated with this drug had a significantly shorter duration of disease development compared to those who received alternative treatments, emphasizing the need for ongoing monitoring of treatment strategies.
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Heterocycle derived moieties, namely, -(4-methoxyphenyl)-1-(1-pyrrol-2-yl)methanimine (MPM), 1-(furan-2-yl)--(4-methoxyphenyl)methanimine (FMM), and -(4-methoxyphenyl)-1-(thiophen-2-yl)methanimine (MTM), were synthesized followed by analysis of their structural aspects using FTIR and H NMR spectroscopic techniques. The corrosion retarding abilities of the same were distinguished by gravimetric and certain electrochemical measures for mild steel in 0.5 M HSO, and MTM was obtained with maximum inhibition efficiency of 97.

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Capsicum is generally infested with many biotic agents mainly sucking insects, among them the major is aphid (. Chemical management is one of the most common strategies for their management. However, there are no recommended insecticides for insect management in polyhouse.

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Objective: To evaluate the effect of continuous arch and piggyback mechanics in a straight wire appliance (SWA) for the alignment of buccal and variably vertically positioned maxillary canines.

Methods: A three-dimensional finite element model with near-normal occlusion and buccal and vertically displaced maxillary canines was used. Two groups were created to simulate two commonly used SWAs techniques, continuous archwire (Group 1) and piggyback models (Group 2).

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Lactose hydrolysed concentrated milk was prepared using β-galactosidase enzyme (4.76U/mL) with a reaction period of 12 h at 4 °C. Addition of polysaccharides (5 % maltodextrin/β-cyclodextrin) to concentrated milk either before or after lactose hydrolysis did not result in significant differences (p > 0.

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The considerable value of whey is evident from its significant potential applications and contributions to the functional food and nutraceutical market. The by-products were individually obtained during functional and novel soy cheese production using defined lactic acid bacterial strains of Sikkim Himalaya's traditional . Hydrolysis of substrate proteins by starter proteinases resulted in a comparable peptide content in whey and soy whey which was associated with antioxidant and ACE inhibition potential.

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Introduction: Goat milk has poorer fermentation characteristics due to the absence or only traces of αs1-casein, due to which goat yoghurt contains a less dense gel structure. Moreover, the fermentation characteristics of the milk vary between the breeds of the same species. Therefore, it becomes imperative to explore a few metabolites which could regulate the techno-functional properties of goat yoghurt.

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, the wheat seed gall nematode, causes the 'ear-cockle' or seed gall disease of wheat (), leading to an extensive decline of yield (30-70%) in underdeveloped wheat cultivating countries of the world. The nematode is known to survive in anhydrobiotic conditions for up to 32 years. Here, we present the first transcriptome assembly of , which will be a valuable resource for understanding the genes responsible for nematode survival and above-ground plant parasitism.

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Article Synopsis
  • Inflammatory bowel disease (IBD) involves chronic inflammation in the intestines due to an improper immune response to gut microbes, particularly in genetically predisposed individuals.
  • Reactive oxygen species (ROS), produced by NADPH oxidases (NOX), play crucial roles in gut defense and barrier maintenance, with mutations in NOX linked to IBD and disruptions in the mucus layer being significant in its development.
  • Analysis of the mucin O-glycome in mice with NOX inactivation revealed new glycan structures and variations in glycan composition, indicating that NOX activity influences mucin glycosylation, potentially worsening intestinal dysbiosis and inflammation.
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Background: This study was conducted to assess the prevalence of dental caries, tobacco usage, and associated risk factors for dental caries in patients who visited a government hospital in Western, Nepal.

Methods: This analytical cross-sectional study was conducted from January to April 2022. Patients above 18 years visiting the dental OPD of a government hospital, and who had provided informed consent were enrolled in the study using a convenience sampling technique.

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Goat milk has achieved significant place in human diet owing to its enormous therapeutic properties. There exists a scope of value-addition of goat milk to potentiate its health benefits by incorporating herbs and plants. ( ), a traditional medicinal plant with rich bioactive composition, can enhance the bioactive properties and shelf-life of goat milk.

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Boron nitride has gained wide-spread attention globally owing to its outstanding characteristics, such as a large surface area, high thermal resistivity, great mechanical strength, low density, and corrosion resistance. This review compiles state-of-the-art synthesis techniques, including mechanical exfoliation, chemical exfoliation, chemical vapour deposition (CVD), and green synthesis for the fabrication of hexagonal boron nitride and its composites, their structural and chemical properties, and their applications in hydrogen production and environmental remediation. Additionally, the adsorptive and photocatalytic properties of boron nitride-based nanocomposites for the removal of heavy metals, dyes, and pharmaceuticals from contaminated waters are discussed.

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The current study reported a facile co-precipitation technique for synthesizing novel NiCoS/chitosan nanocomposite. The photocatalytic activity of the prepared nanocomposite was evaluated using congo red (CR) dye as a target pollutant. The central composite design was employed to examine the impact of different reaction conditions on CR dye degradation.

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