Publications by authors named "Ashish Bosco"
Article Synopsis
- The study aimed to create a demographic profile of stroke patients in the emergency department, assess their treatment with thrombolysis, and track their outcomes until discharge or death.
- The research included 216 patients, mostly male, with the majority suffering from ischemic strokes, while only a small percentage presented within the critical time frame for treatment.
- Findings highlighted that many patients faced challenges in early hospital presentation, impacting treatment efficacy and outcomes, indicating a need for better awareness and intervention strategies for stroke management.
Although antimicrobials are the cornerstone of neonatal sepsis management, adjunctive therapies are required to improve outcomes. The aim of our study was to evaluate the effect of exchange transfusion (ET) on mortality (primary outcome) in neonatal sepsis, as well as on immunoglobulin, complement and neutrophil levels and assess its complications (secondary outcomes). Databases searched include PubMed, NCBI, Google Scholar, CINHAL, Ovid and Scopus.
View Article and Find Full Text PDFObjective: To elucidate characteristics among neonates and their mothers who were discharged against medical advice (DAMA), providers' perspectives on DAMA and the effect of an intervention to reduce DAMA in a tertiary care hospital in South India.
Methods: We conducted a mixed-methods study to identify neonates at risk of DAMA. We reviewed charts of neonates and their mothers who were DAMA and conducted logit regression analysis to calculate adjusted odds ratios (aOR) and 95% confidence intervals (CI) to determine associations with DAMA.
Article Synopsis
- India has a high prevalence of enteric fever, and a study at St. John's Medical College Hospital analyzed differences in clinical presentations between adult and pediatric patients over one year.
- Out of 113 cases, young adults (16-30 years) and children (<15 years) made up the majority, with common issues like anemia and unusual symptoms including arthritis and repeat infections.
- The findings suggest that enteric fever presents with variable clinical features due to host and environmental factors, emphasizing the need for better surveillance and monitoring of the disease to improve treatment and prevention strategies.
Article Synopsis
- The study conducted genomic surveillance of enteric fever pathogens in South India, a first for the region, analyzing blood culture-confirmed cases over one year.
- Blood samples from hospitalized patients at St John's Medical College Hospital were used to identify 101 S. enterica Typhi and 14 S. Paratyphi A, with most isolates showing resistance to fluoroquinolones.
- Findings revealed a concerning rise of a fluoroquinolone-resistant S. Typhi clone linked to treatment failures, emphasizing the urgent need for enhanced surveillance and coordinated public health strategies to combat antimicrobial resistance and improve hygiene and vaccination efforts in the region.*
Resilience in Wives of persons with Alcoholism: An Indian exploration.
Indian J Psychiatry
January 2018
Context: Mental health has currently shifted focus from "deficit" to strength-based approaches such as Resilience. Coping styles and personality factors have been well studied in Wives of persons with Alcoholism (WopA) but not Resilience. Alcohol dependence in spouse is seen as an adversity.
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