Successful treatment of thyroid storm with plasmapheresis in a patient with methimazole-induced agranulocytosis.

Objective: To report a case of a patient with Graves disease presenting with agranulocytosis induced by methimazole, with subsequent thyroid storm and successful therapeutic use of plasmapheresis.

Methods: The clinical features and laboratory findings in a patient with agranulocytosis and thyroid storm are presented, and the available literature on utilization of plasmapheresis in the setting of thyrotoxicosis is reviewed.

Results: A 40-year-old Vietnamese woman with Graves disease was admitted with methimazole-induced agranulocytosis.