Effectiveness of Zinc Supplementation on Lithium-Induced Alterations in Thyroid Functions.

Lithium is an integral drug used in the management of acute mania, unipolar and bipolar depression, and prophylaxis of bipolar disorders. Thyroid abnormalities have been associated with treatment with lithium. Zinc is an essential trace element that plays a role in several biological activities.

Study of life style habits on risk of type 2 diabetes.

Background: Diabetes mellitus has become one of the great epidemics of our time.

Aim: Characterized by derangement of carbohydrate, protein and fat metabolism. Diabetic patients may have some other habits like drinking, smoking, lack of physical activity.

Supplementation of zinc mitigates the altered uptake and turnover of 65Zn in liver and whole body of diabetic rats.

Diabetes is a life threatening disease and its onset is linked with both environmental and genetic factors. Zinc metabolism gets altered during diabetes and results in many complications. The present study was designed to elucidate the effects of zinc supplementation on the biokinetics of (65)Zn in whole body, liver and its biodistribution in diabetic rats.

Effect of zinc on hepatic drug metabolism under ethanol toxicity.

The effects of zinc on drug-metabolizing enzymes in the liver were examined in male Wistar rats following ethanol intoxication. Rats were orally fed 3 mL of 30% ethanol daily for either two, four, or eight weeks and were orally administered zinc sulfate (ZnSO4.7H2O) at a dose level of 227 mg/L.